Fifteen native taxa are reported as new to either District of Keewatin (now Nunavut in part) or District of Mackenzie (Nunavut contains the northeastern portion): Aster puniceus, Astragalus eucosmus, Astragalus eucosmus f. albinus, Carex media, Epilobium latifolium f. albiflorum, Eriophorum viridi-carinatum, Erysiumum pallasii, Moneses uniflora, Najas flexilis, Potamogeton obtusifolius, Salix arctica x glauca, Salix glauca ssp. callicarpae, Salix myrtillifolia, Salix rotundifolia, Shepherdia canadensis, taxa are new to Northwest Territories overall. Significant range extensions for 157 native taxa are included.

Based on field reconnaissance since the publication of Flora of the Continental Northwest Territories in 1980, particularly in the District of Keewatin and northeastern District of Mackenzie (Nunavut) and Nahanni National Park, information is provided on geographically significant plant occurrences. One new taxon, Polemonium boreale forma albiflorum, is described, fourteen native taxa are reported as new to the region: Carex hoodii, C. microptera, C. petasata, Corispermum hookeri, C. ochotense, Danthonia spicata, Draba stenoloba, Erysisnum coarctatum, Halenia deflexa, Polygonum fowleri, P. ramosissimum, Salix rotundifolia ssp. rotundifolia, Silene uralensis ssp. ogilviensis, and Vaccinium ovalifolium. Five introduced taxa, Crepis tectorum, Corispermum villosum, Deschampsia elongata, D. incisa var. incisa, and Medicago sativa ssp. falcata are new to the flora of the region. Two native taxa, Danthonia intermedia and Potentilla porsildiorum are deleted from the flora and Ranunculus aquatilis var hispidulus is placed in synonymy. Significant range extensions for 125 native and one introduced taxon are included.