In conjunction with an overall increased attention toward cost and time savings, the push to modernize instrumentation is now enabling the otolaryngologist to keep both the medical and surgical treatment of rhinologic patients, particularly those with chronic disease, within the office setting.

Mammary analogue secretory carcinoma (MASC) of the salivary gland is a recently described, rare, and unique diagnostic entity. This unusual lesion corresponds histopathologically and cytogenetically to secretory carcinoma of the breast. MASC of the salivary gland displays overlapping features of both mammary secretory carcinoma and acinic cell carcinoma (AciCC). This tumor is characterized by the chromosomal translocation (12;15) (p13;q25), which results in the fusion gene ETV6-NTRK3. We report a rare case of MASC presenting as a left parotid mass in a 48 year-old male, which was confirmed by ETV6 gene rearrangement studies by Fluorescence in situ hybridization (FISH). MASC, while rare, should be considered in the differential diagnosis of salivary gland lesions.

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