With the recent commercialization of fifth-generation mobile communication systems (5G), wireless communications are being used in various fields. Accordingly, the number of situations in which sensitive information, such as personal data is handled in wireless communications is increasing, and so is the demand for confidentiality． To meet this demand, we proposed a chaos-based radio-encryption modulation that combines physical layer confidentiality and channel coding effects, and we have demonstrated its effectiveness through computer simulations. However, there are no demonstrations of performances using real signals. In this study, we constructed a transmission system using Universal Software Radio Peripheral, a type of software-defined radio, and its control software LabVIEW. We conducted wired transmission experiments for the practical use of radio-frequency encrypted modulation. The results showed that a gain of 0.45 dB at a bit error rate of 10 was obtained for binary phase-shift keying, which has the same transmission efficiency as the proposed method under an additive white Gaussian noise channel. Similarly, a gain of 10 dB was obtained under fading conditions. We also evaluated the security ability and demonstrated that chaos modulation has both information-theoretic security and computational security.