I nvasive meningococcal disease (IMD) remains a major cause of death and permanent disability worldwide (1). IMD is caused by Neisseria meningitidis, a gram-negative diplococcus bacterium, which frequently colonizes the human nasopharynx and might spread from person-to-person by respiratory droplets or direct contact with respiratory secretions. However, only a small proportion of persons will show development of invasive infection, typically with serogroups A, B, C, W or Y (2). IMD is most common in the dry winter and spring, in overcrowded households, and in persons who have preceding upper respiratory tract infections, splenectomy, and in the presence of terminal complement deficiencies (3,4).
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