BACKGROUND Myocardial Infarction (MI) is the term used to describe a state of myocardial necrosis secondary to an acute interruption of the coronary blood supply. 1 It is one of the manifestations of coronary heart disease leading to morbidity and mortality. 2 World Health Organization (WHO) has declared cardiovascular disease as a modern epidemic. 3 Most of the myocardial infarctions results due to disruption in the vascular endothelium associated with atherosclerotic plaque, which in turn stimulates the formation of an intracoronary thrombus, which further leads to occlusion of coronary artery blood flow, if this occlusion persists for more than 20 minutes can results in irreversible myocardial cell damage and even cell death. Severity of the condition is dependent on three factors-the level of occlusion, length of time of occlusion and presence or absence of collateral circulation. Rupturing of the plaque causes complete coronary occlusion, which usually results in STEMI. This arises most often from a plaque that previously caused less than 50% lumen occlusion. 4 Clinical diagnosis as well as diagnostic classification is commonly based on electrocardiographic findings to differentiate between the two types of MI. There are mainly two types, STEMI and NSTEMI. Complications of acute MI are many, which in turn leads to high incidences of mortality, but among all arrhythmias, cardiogenic shock and heart failure are found to be commonly associated with it along with electrolyte disturbances. The aim of the study is to observe the prevalence of various electrolyte (Na, K, CL and Mg) imbalances along with complication of cardiogenic shock, arrhythmias and heart failure in the patients of acute myocardial infarction. MATERIALS AND METHODS This is a prospective study in which the 100 patient admitted with signs and symptoms of acute myocardial infarction diagnosed clinically both males and females were selected over 1 year. Patients presented with symptoms of AMI within 48 hours of onset with history of chest discomfort, ECG changes of acute myocardial infarction and rise of cardiac enzymes.

BACKGROUNDThe term "arrhythmia" refers to any change from the normal sequence of electrical impulses. The electrical impulses may happen too fast, too slowly or erratically causing the heart to beat too fast, too slowly or erratically. When the heart doesn't beat properly, it can't pump blood effectively. When the heart doesn't pump blood effectively, the lungs, brain and all other organs can't work properly and may shutdown or be damaged. Normally, the heart's most rapidly firing cells are in the sinus (or sino-atrial or SA) node making that area a natural pacemaker. Under some conditions, almost all heart tissue can start an impulse of the type that can generate a heartbeat. Cells in the heart's conduction system can fire automatically and start electrical activity. This activity can interrupt the normal order of the heart's pumping activity. Secondary pacemakers elsewhere in the heart provide a "backup" rhythm when the sinus node doesn't work properly or when impulses are blocked somewhere in the conduction system. An arrhythmia occurs when the heart's natural pacemaker develops an abnormal rate or rhythm. The normal conduction pathway is interrupted. Another part of the heart takes over as pacemaker.The aim of the study is to observe the prevalence of various electrolyte (Na, K, Cl and Mg) imbalances in complications of arrhythmias. MATERIALS AND METHODSThis is a prospective study in which the patient admitted with signs and symptoms of cardiac arrhythmias diagnosed clinically, 100 cases were selected over 1 year. RESULTSThe serum magnesium, sodium and potassium levels were significantly lower in the AMI patients at baseline and gradually becomes near normal on 4 th day. K and Mg are showing significant difference between pre and post values in males and Mg show significant difference between pre and post values day 1 and day 5 in females with arrhythmia. CONCLUSIONPersistent hyponatraemia is indication of worsening cardiac failure and cardiogenic shock. There is also relationship between serum potassium and QTc interval, so estimation of sodium, potassium, chlorine and magnesium levels in arrhythmia patients can help to assess prognosis.

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