We describe a strain of Lassa virus representing a putative new lineage that was isolated from a cluster of human infections with an epidemiologic link to Togo. This finding extends the known range of Lassa virus to Togo.

Marburg virus (MARV) causes sporadic outbreaks of severe Marburg virus disease (MVD). Most MVD outbreaks originated in East Africa and field studies in East Africa, South Africa, Zambia, and Gabon identified the Egyptian rousette bat (ERB; Rousettus aegyptiacus) as a natural reservoir. However, the largest recorded MVD outbreak with the highest case-fatality ratio happened in 2005 in Angola, where direct spillover from bats was not shown. Here, collaborative studies by the

Two patients with Lassa fever are described who are the first human cases treated with a combination of ribavirin and favipiravir. Both patients survived but developed transaminitis and had prolonged detectable virus RNA in blood and semen, suggesting that the possibility of sexual transmission of Lassa virus should be considered.

No abstract

Case History A 68 years old male patient was admitted with febrile illness in February 2010. His routine work up was inconclusive for diagnosis of common infectious cause of acute febrile illness. He responded to antibiotic treatment. His HIV ELISA (4 th generation of ELISA for HIV 1 and 2; result 0.0 by Enzyme linked fluorescent assay [ELFA]) and Western blot test were negative (27/2/2010). His P24 Antigen assay with ELFA was positive.