Domestic minor sex trafficking is a complex form of oppression and child maltreatment affecting children and adolescents on both the domestic and transnational levels. In the United States, the statistical account of minors who are affected by commercial sex trafficking varies because of the hidden nature of this criminal activity. Symptoms of trauma can result from such factors as forced subjugation, separation from family, and sexual acts with multiple perpetrators. Treatment relevant to this population is necessary for posttrafficking adaptation to society. In this article, we discuss the possible effects of domestic minor sex trafficking, implications for intervention, and directions for future research.