Despite substantial evidence demonstrating a relation between gender-based beliefs and violence against women, there has been little research examining whether sexist attitudes are related to prosocial bystander behavior. Understanding psychosocial influences on bystanders’ behavior could inform bystander training programs on college campuses, and so the current study examined the unique and joint effects of three gender-based attitudes (rape myth acceptance, hostile sexism, and benevolent sexism) and empathy in predicting bystander behavior and perceived barriers to intervention in situations that undergraduates ( N = 500; 70% female; Mage = 18.86 years) had experienced in the prior year. Benevolent sexism was the only gender-based attitude consistently associated with bystander behavior and perceived barriers. After accounting for participant empathy, benevolent sexism uniquely predicted less intervention in post-assault situations, greater perceived barriers in pre- and post-assault situations, and greater Failure to Perceive Responsibility and Skill Deficit barriers across situations. Associations between gender-based attitudes and bystander behavior also differed for men and women, with rape myth acceptance predicting greater Failure to Perceive Responsibility barriers and benevolent sexism predicting greater Skill Deficit barriers for women but not men. These results suggest that existing bystander education programs can be improved by explicitly addressing benevolent sexist beliefs and promoting empathy for victims of assault.

OBJECTIVES/GOALS: Neuroimaging research has found that childhood maltreatment is related to reduced activation of the nucleus accumbens. The long-lasting impact of this relationship is not as well understood. This study aims to explore the association between childhood emotional neglect and reward-related functional connectivity in an adult trauma sample. METHODS/STUDY POPULATION: Participants (N=169, M age=, 32.2; SD=10.3; women=94) experienced a traumatic injury and were recruited from a Level I Trauma Center. Two-weeks post injury, participants completed the Childhood Trauma Questionnaire (emotional neglect M=10.6; SD=5.2), a self-reported, retrospective account of childhood maltreatment, and underwent a resting-state functional magnetic resonance imaging (fMRI) scan. Whole-brain resting-state left and right nucleus accumbens connectivity analyses were completed using the CONN Toolbox. RESULTS/ANTICIPATED RESULTS: Whole-brain left nucleus accumbens connectivity analyses revealed one significant region (angular gyrus (AG); p DISCUSSION/SIGNIFICANCE: Results suggest that childhood emotional neglect is related to nucleus accumbens connectivity and a brain region associated with memory, attention, and theory of mind in adult survivors of trauma. Early life emotional neglect may be contributing to heightened baseline reward sensitivity–particularly for social rewards (implicated by the AG).

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