Research on soft-biometrics showed that privacy-sensitive information can be deduced from biometric data. Utilizing biometric templates only, information about a persons gender, age, ethnicity, sexual orientation, and health state can be deduced. For many applications, these templates are expected to be used for recognition purposes only. Thus, extracting this information raises major privacy issues. Previous work proposed two kinds of learning-based solutions for this problem. The first ones provide strong privacy-enhancements, but limited to pre-defined attributes. The second ones achieve more comprehensive but weaker privacy-improvements. In this work, we propose a Privacy-Enhancing face recognition approach based on Minimum Information Units (PE-MIU). PE-MIU, as we demonstrate in this work, is a privacy-enhancement approach for face recognition templates that achieves strong privacy-improvements and is not limited to pre-defined attributes. We exploit the structural differences between face recognition and facial attribute estimation by creating templates in a mixed representation of minimal information units. These representations contain pattern of privacy-sensitive attributes in a highly randomized form. Therefore, the estimation of these attributes becomes hard for function creep attacks. During verification, these units of a probe template are assigned to the units of a reference template by solving an optimal best-matching problem. This allows our approach to maintain a high recognition ability. The experiments are conducted on three publicly available datasets and with five state-of-the-art approaches. Moreover, we conduct the experiments simulating an attacker that knows and adapts to the systems privacy mechanism. The experiments demonstrate that PE-MIU is able to suppress privacy-sensitive information to a significantly higher degree than previous work in all investigated scenarios. At the same time, our solution is able to achieve a verification performance close to that of the unmodified recognition system. Unlike previous works, our approach offers a strong and comprehensive privacy-enhancement without the need of training.

Most genomes harbor a large number of transposons, and they play an important role in evolution and gene regulation. They are also of interest to clinicians as they are involved in several diseases, including cancer and neurodegeneration. Although several methods for transposon identification are available, they are often highly specialised towards specific tasks or classes of transposons, and they lack common standards such as a unified taxonomy scheme and output file format. We present TransposonUltimate, a powerful bundle of three modules for transposon classification, annotation, and detection of transposition events. TransposonUltimate comes as a Conda package under the GPL-3.0 licence, is well documented and it is easy to install through https://github.com/DerKevinRiehl/TransposonUltimate. We benchmark the classification module on the large TransposonDB covering 891,051 sequences to demonstrate that it outperforms the currently best existing solutions. The annotation and detection modules combine sixteen existing softwares, and we illustrate its use by annotating Caenorhabditis elegans, Rhizophagus irregularis and Oryza sativa subs. japonica genomes. Finally, we use the detection module to discover 29 554 transposition events in the genomes of 20 wild type strains of C. elegans. Databases, assemblies, annotations and further findings can be downloaded from (https://doi.org/10.5281/zenodo.5518085).

MotivationMost genomes harbor a large number of transposons, and they play an important role in evolution and gene regulation. They are also of interest to clinicians as they are involved in several diseases, including cancer and neurodegeneration. Although several methods for transposon identification are available, they are often highly specialised towards specific tasks or classes of transposons, and they lack common standards such as a unified taxonomy scheme and output file format. Moreover, many methods are difficult to install, poorly documented, and difficult to reproduce.ResultsWe present TransposonUltimate, a powerful bundle of three modules for transposon classification, annotation, and detection of transposition events. TransposonUltimate comes as a Conda package under the GPL-3.0 licence, is well documented and it is easy to install. We benchmark the classification module on the large TransposonDB covering over 891,051 sequences to demonstrate that it outperforms the currently best existing solutions. The annotation and detection modules combine sixteen existing softwares, and we illustrate its use by annotating Caenorhabditis elegans, Rhizophagus irregularis and Oryza sativa subs. japonica genomes. Finally, we use the detection module to discover 29,554 transposition events in the genomes of twenty wild type strains of Caenorhabditis elegans.AvailabilityRunning software and source code available on https://github.com/DerKevinRiehl/TransposonClassifierRFSB. Databases, assemblies, annotations and further findings can be downloaded from https://cellgeni.cog.sanger.ac.uk/browser.html?shared=transposonultimate.