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COVID-19 cases have surpassed the 109 + million markers, with deaths tallying up to 2.4 million. Tens of thousands of papers regarding COVID-19 have been published along with countless bibliometric analyses done on COVID-19 literature. Despite this, none of the analyses have focused on domain entities occurring in scientific publications. However, analysis of these bio-entities and the relations among them, a strategy called entity metrics, could offer more insights into knowledge usage and diffusion in specific cases. Thus, this paper presents an entitymetric analysis on COVID-19 literature. We construct an entity–entity co-occurrence network and employ network indicators to analyze the extracted entities. We find that ACE-2 and C-reactive protein are two very important genes and that lopinavir and ritonavir are two very important chemicals, regardless of the results from either ranking.

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Azo dye is a kind of most commonly used dyes in related industries. As the discharge from azo dye related industries is commonly found with high salinity and temperature, halo-thermophlic microbes able to decolorize azo dyes are required. Consortium HR enriched under 5% salinity and 50°C in this study was mainly composed of Ueribacillus (70.4%), Tepidimicrobium (11.7%) and Clostridium (10.4%). The influence of salinity (1% to 10%) and pH (6 to 10) on the decolorization process were further measured. Meanwhile, consortium HR was identified with ability to decolorize several kinds of azo dyes and the phytotoxicity of the metabolic intermediates was decreased with the incubation time. All the results indicate that consortium HR has a good potential in the decolorization of azo dyes in hypersaline, high temperature and week alkaline conditions.