Papillon-Lefèvre syndrome (PLS) an autosomal recessive disorder characterized by diffuse transgradient palmar-plantar hyperkeratosis, with premature loss of deciduous and permanent teeth, along with the calcification of the dura mater. This results in teeth radiographically appearing as “floating” in the soft tissue. Genetic studies of patients with PLS have mapped the major gene locus to chromosome 11q24-q21 and revealed mutation and loss of function of the cathepsin gene. It affects 1- 4 people per 1 million population with no gender or racial predilection. Dermatological manifestations, usually occurs before four years of age, include hyperkeratosis of palms and soles, nail dystrophy, hyperhidrosis and keratinization on elbows and knees with the lesions appearing as white, yellow-like or red plaques or patches that then develop cracks, crusts, or deep fissures. KEYWORD: Papillon-lefevre syndrome, hyperkeratosis HOW TO CITE: Zalan AK, Zubairy KK, Maxood A, Niazi M, Zaman H, Gul A, Anser M. Papillon lefevre syndrome: Diagnosis and management in two affected siblings – A case report. J Pak Dent Assoc 2020;29(4):264-268.

Most common form of dental trauma in children are the fractures of crown mainly in anterior teeth. A case of complicated crown fracture treated with Cvek pulpotomy using MTA followed by fragment re-attachment with careful follow-up is presented here. Tooth fragment re-attachment provides feasible conservative alternative approach to restore esthetics and tooth function. Successful outcomes have been shown by the long term follow up of the treatment with the preservation of pulp vitality and continued development of root. Clinical results have also shown good esthetics and functional results of presented technique. KEYWORDS: Complicated crown fracture, Cvek pulpotomy, MTA, fragment re-attachment HOW TO CITE: Zalan AK, Zubairy KK, Zaman H, Maxood A, Gul A, Anser M. MTA cvek pulpotomy followed by fragment re-attachment in traumatized young permanent maxillary left central incisor – A case report. J Pak Dent Assoc 2021;30(1):70-73.

OBJECTIVES: To correct dental origin anterior crossbite by placement of Glass Ionomer cement occlusal stops on mandibular first permanent molars for maximum of two weeks. METHODOLOGY: 16 patients (age: 7-11 years) with dental anterior crossbite were treated by placement of Glass Ionomer cement occlusal stops on mandibular first permanent molars for maximum of 2 weeks to create 1mm anterior open bite. The patients were then recalled after 1 month, 3 months and 6 months for follow up visits. Fisher’s exact test applied using SPSS version # 25. RESULTS: 13 out of 16 patients were treated successfully within two weeks of placement of occlusal stops. Follow-up at six months showed no relapse in any of the corrected cases. CONCLUSION: Placement of glass ionomer cement occlusal stops for two weeks on mandibular first permanent molars is an easy approach to correct dental anterior crossbite. KEYWORDS: Crossbite, Malocclusion, Glass ionomer cement, Corrective orthodontics