We aimed to describe the characteristics and care of participants with diabetes during Ramadan in the Middle East and North Africa (MENA). Methods: In this prospective, observational study, we analysed the number of fasted days, number of participants fasting, glycemic control, rate of hypoglycemic events, and lifestyle patterns for participants with T2DM during Ramadan 2016. Results: The population included 1749 participants with T2DM. The mean (SD) duration of fasting was 27.7 (5.0) days, and 57.3% of participants fasted for the full duration of Ramadan. Following Ramadan, a significant improvement in HbA1c, FPG, and PPG was observed (p < 0.0001). Confirmed hypoglycemia increased significantly from before to during Ramadan (incidence: 4.9% vs. 10.4%, p < 0.001; adverse events: 0.11 vs. 0.22 events/month/participant, p < 0.001) and was dependent on the treatment regimen. Severe hypoglycemia incidence was 0.2% before versus 0.9% during Ramadan (p = 0.031), whereas adverse events

Introduction: To describe the characteristics and care of participants with type 1 diabetes during Ramadan in the Middle East and North Africa. Methods: The DAR-MENA (Diabetes and Ramadan-Middle East and North Africa) study was a prospective, observational study of adults with type 1 and type 2 diabetes who were Muslim and did/did not intend to fast during Ramadan 2016. Baseline data were collected 6 weeks prior to Ramadan, with a follow-up visit 1-2 months after Ramadan. This is the analysis of the population with type 1 diabetes. Measurements included proportion who fasted, reasons for fasting and not fasting, changes in diabetes treatment, hypoglycemic events, and proportion with access to diabetes education. Results: Of 136 participants with type 1 diabetes, 76.9% (100/130) fasted for at least 1 day, 72.3% (94/130) fasted for at least 15 days, and 48.5% (63/130) fasted for 30 days. The majority (63.0%, 63/100) reported personal decision as a reason to fast. Fear of diabetic complications (58.6%, 17/29) and previous complications related to fasting Enhanced Digital Features To view enhanced digital features for this article go to https://doi.org/10.6084/ m9.figshare.11860932.

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Backgroud : Insulin resistance is a pathogenic hallmark of type 2 diabetes mellitus (T2DM).Serum ferritin, a predominant iron-storage protein and a biomarker of iron stores, are elevated in persons with prevalent diabetes as compared with non-diabetic controls and correlate with impaired fasting glucose levels.High ferritin levels have been associated with the metabolic syndrome and measures of insulin resistance .The aim of the current study : is to measure Serum Ferritin in patients with type 2 diabetes in Beni-Suef governorate and to study the relationship between serum Ferritin and Insulin Resistance. Patients and Methods : This study involved 40 patients with type 2 diabetes (24 females and 16 males) and 20 healthy adults (12 females and 8 males) served as a control group. All groups included in this study were subjected to Full History Taking, Clinical Examination including (BMI & Waist Circ.) and Laboratory Investigation including ( FPG, HbA1c, Serum Ferritin and Fasting Serum Insulin & measuring HOMA-IR).Results : Ferritin showed a statistically significant correlation with Waist Circ., FPG, HbA1c, Fasting Serum Insulin and Insulin Resistance (HOMA-IR) in the diabetic group (P < 0.05) .Conclusion: Serum ferritin can be used as a marker of insulin resistance syndrome in diabetics