Background: Unhappiness, stress, and burnout will often lead to low academic performance among dental students. Perseverance and passion for long-term goal, known as grit, could overcome these despondent emotions. Our Study is looking at whether grit should be added as another domain during the interview process. The main objective of this study was to determine the association between grit and happiness among Universiti Teknologi MARA (UiTM) dental students. In addition to that, the prevalence of gritty and happy dental students in UiTM was also determined and compared across the years of study. Methods: This was a cross-sectional study. Validated Short Grit Scale (Grit-S) and Pemberton Happiness Index (PHI) were distributed to all 409 undergraduate dental students in Faculty of Dentistry, UiTM through their class representatives. Scores for both grit and happiness were calculated according to their instruction manual. Data were analyzed using SPSS Version 25 by descriptive analysis, oneway ANOVA, independent t-test, Pearson's correlation, and linear regression.Result: Two hundred sixty-six students returned the answered questionnaires, yielding a response rate of 65%. Prevalence of gritty and happy UiTM dental students was found to be at 79% and 41%, respectively. There was a significant positive fair linear correlation between grit and happiness among dental students (r = 0.225, p < 0.001). A significantly higher happiness score is observed among gritty student (p < 0.001). Conclusion: While this study demonstrated high prevalence of grit, prevalence of happiness among UiTM dental students was low. Higher grit score had a positive impact on happiness score among dental students in UiTM. For this reason, grit may be considered as an additional element in selecting upcoming dental students.