Diabetic Retinopathy (DR) harm retinal blood vessels in the eye causing visual deficiency. The appearance and structure of blood vessels in retinal images play an essential part in the diagnoses of an eye sicknesses. We proposed a less computational unsupervised automated technique with promising results for detection of retinal vasculature by using morphological hessian based approach and region based Otsu thresholding. Contrast Limited Adaptive Histogram Equalization (CLAHE) and morphological filters have been used for enhancement and to remove low frequency noise or geometrical objects, respectively. The hessian matrix and eigenvalues approach used has been in a modified form at two different scales to extract wide and thin vessel enhanced images separately. Otsu thresholding has been further applied in a novel way to classify vessel and non-vessel pixels from both enhanced images. Finally, postprocessing steps has been used to eliminate the unwanted region/segment, non-vessel pixels, disease abnormalities and noise, to obtain a final segmented image. The proposed technique has been analyzed on the openly accessible DRIVE (Digital Retinal Images for Vessel Extraction) and STARE (STructured Analysis of the REtina) databases along with the ground truth data that has been precisely marked by the experts.
The visual exploration of retinal blood vessels assists ophthalmologists in the diagnoses of different abnormalities of the eyes such as diabetic retinopathy, glaucoma, cardiovascular ailment, high blood pressure, arteriosclerosis, and age-related macular degeneration. The manual inspection of retinal vasculature is an extremely challenging and tedious task for medical experts due to the complex structure of an eye, tiny blood vessels, and variation in vessels width. Several automatic retinal vessels extraction techniques have been proposed in contemporary literature, which assist ophthalmologists in the timely identification of an eye disorders. However, due to the fast evolution of such techniques, a comprehensive survey is needed. This survey presents a comprehensive review of such techniques, strategies, and algorithms presented to date. The techniques are classified into logical groups based on the underlying methodology employed for retinal vessel extraction. The performance of existing techniques is reported on the publicly accessible datasets in term of various performance measures, providing a valuable comparison among the techniques. Thus, this survey presents a valuable resource for researchers working toward automatic extraction of retinal vessels.
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