Introduction. Solitary extramedullary plasmacytoma (SEP) is a rare neoplasm that is derived from monoclonal proliferation of plasma cells in the soft tissues or organs arising outside the bone marrow. It is present in about 3% of all plasma cell tumors and originates mainly from the upper respiratory tract and nasopharynx. Involvement of the esophagus is exceptionally seen in cases of SEP. Case Presentation. We report a novel case of a 74-year-old male patient attended with a 6-month history of hiccupping further associated with dysphasia and weight loss all caused by esophageal plasmacytoma. Histological and immunohistochemical examination of the tumor confirmed the diagnosis of plasmacytoma. Workup for the multiple myeloma came out to be negative, thus confirming the diagnosis of SEP. The patient was treated with radiotherapy alone, leading to complete remission (at 30 months of follow-up). Conclusion. Esophageal plasmacytoma, an exceptional presentation of extramedullary plasmacytoma, should be kept in mind while dealing with patients presenting with intractable hiccups.
A study was carried out in three months , to show the prevalence of tick infestation among feedlode calves in Al-Manathera region in Al-Najaf Al-Alashraf city . the infestation rate was 43.9 % (354 from 806 ) .Severity of infestation of calves were 23 % with 5-10 tick/animal which represent the highest rate , and 6 % with 21-25 tick/animal . which represent the lowest rate . The most infested area are perineum in a rate of 36.72 % ,while the less infested area are testis in a rate of 5.36 % . two genus were identified , which are Hyalomma spp. and Ixodes spp. In a rate of 43.7 % (146 tick from 404 ) and 56.2 % (258 tick from 404).
Background: Multiple myeloma is a hematologic malignancy characterized by clonal proliferation of plasma cells, mainly in bone marrow. Extramedullary disease is reported in many cases and may occur at diagnosis, at progression, or during relapse phase. Pericardial involvement is a rare condition that usually occurs with advanced-stage disease. We report a rare case of plasma cell-based pericardial effusion with cardiac tamponade as a form of presentation of multiple myeloma.Case presentation: A 76-year-old woman was admitted to the emergency department for worsening shortness of breath, on segmental examination, she had dyspnea, engorged jugulars, muffled heart sounds and lower limb edema. A Chest X-ray demonstrated cardiomegaly with a mild left pleural effusion, laboratory data showed immunoglobulin G lambda, diagnosis of plasma cell-based pericardial effusion was established by pericardial fluid cytology. The patient received systemic chemotherapy, according to Melphalan-Prednisone and thalidomid protocol. Conclusion: Multiple myeloma with cardiac effusion should be considered for differential diagnosis of patients with recurrent and unexplained pericardial effusions.
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