Introduction. Genetic testing services for disease prediction, drug responses, and traits are commercially available by several companies in Korea. However, there has been no evaluation study for the accuracy and usefulness of these services. We aimed to compare two genetic testing services popular in Korea with 23andMe service in the United States. Materials and Methods. We compared the results of two persons (one man and one woman) serviced by Hellogene Platinum (Theragen Bio Institute), DNAGPS Optimus (DNAlink), and 23andMe service. Results. Among 3 services, there were differences in the estimation of relative risks for the same disease. For lung cancer, the range of relative risk was from 0.9 to 2.09. These differences were thought to be due to the differences of applied single nucleotide polymorphisms (SNPs) in each service for the calculation of risk. Also, the algorithm and population database would have influence on the estimation of relative disease risks. The concordance rate of SNP calls between DNAGPS Optimus and 23andMe services was 100% (30/30). Conclusions. Our study showed differences in disease risk estimations among three services, although they gave good concordance rate for SNP calls. We realized that the genetic services need further evaluation and standardization, especially in disease risk estimation algorithm.

ally [2]. Respiratory infections can be caused by any of the 26 respiratory viruses currently known [2, 3]. Several children with respiratory illnesses are diagnosed with viral co-infections with at least 5 concomitant respiratory virus species [3]. Conventional detection methods for respiratory virus infection include virus culture, antigen detection, and serology, which are time-consuming, labor-intensive, and with low sensitivity [4]. These methods yield an overall virus detection rate of <40% in children with lower respiratory illnesses (acute wheezing/asthma and pneumonia) [3]. Various nucleic acid-based amplification technologies have been used to detect respiratory viruses, such as polymerase chain reaction (PCR), nucleic acid sequence-based ampli cation, transcription-mediated ampli cation, strand displacement ampli cation, loop-mediated isothermal ampli cation, rolling circle amplication, helicase-dependent ampli cation, and multiplex ligation

A 73-yr-old male presented with fever, vomiting, and dyspnea.His medical history included a prior cerebrovascular attack and multiple complications caused by hemiplegia, including recurrent urinary tract infections and pressure sores requiring continuous medical care.On the day of admission, his body temperature, pulse rate, respiratory rate, and blood pressure were 40.4°C, 108/min, 39/min, and 170/90 mmHg, respectively. Abdominal examina-tion revealed diffuse tenderness and guarding with absence of bowel sounds. The initial laboratory test data were as follows: Hb, 14.9 g/dL; white blood cell count, 7,250/μL (neutrophils, 78.0%); and platelets, 110,000/μL. His procalcitonin level was elevated to 28.46 ng/mL. Sputum and urine cultures were negative. PCR to detect Eggerthella lenta is an anaerobic, non-spore-forming, non-motile, gram-positive bacillus that can be isolated from human feces and a few other clinical specimens. Bacteremia caused by the organism is rare but, when present, is always of clinical significance. E. lenta is an emerging pathogen that has been under-recognized because of difficulties with its laboratory identification. Few reports on E. lenta infections and the optimal treatment thereof are available. We describe a case of bacteremia caused by E. lenta in an elderly patient with an intra-abdominal abscess. We also review the current literature.