No abstract

The current coronavirus pandemic is unparalleled in recent memory and fundamentally unique. It has been more than a century since humanity fought the Spanish flu pandemic. That widespread disease devastated a World War I-ravaged population when there was a relative paucity of medical knowledge. Coronavirus, on the other hand, is now befalling upon a developed world with advanced infrastructure and health systems; wherein access to medical information and technology is abundant. Yet, it has proven to be a destroyer of economies and populations without geographical partiality. This article is meant to be a broad analysis of the virus, which is causing global disruption from both a historical and clinical perspective. We are receiving new facts and figures daily. Thus, this review is up-to-date as much as it can be and meant to serve as a general knowledge base for all involved in the fight.

Background SARS-CoV-2 antibody testing shows the prevalence of COVID-19 disease in different communities and has epidemiological significance. Methods SARS-CoV-2 IgM and IgG were tested in 319 patients, staff and visitors of a primary care clinic in Las Vegas, NV on a continuous as-requested basis. Results Prevalence of SARS-CoV-2 antibodies was 3.76% in a primary care office in Las Vegas, NV. Positivity of IgM was 0.31% and IgG 3.44%. The most common symptoms reported amongst those who tested positive were cough, shortness of breath and loss of smell and taste. The most common comorbidities included hypertension, chronic lung disease, seasonal allergies, and type 2 diabetes mellitus, in that order. Conclusion Prevalence was 2.3% in Washoe County, NV in June 2020 and 3.76% in Clark County, NV in April-June 2020. This has important implications for heavily populated urban areas.