Digital fabrication leads architects and structural engineers to modify the design optimisation methodology. The designers, as never before, are facing new technologies developed in the search for new materials based, among others, on wood components and the improvement of manufacturing methods at the same time. In this process, the material and manufacturing technology adjustment to desired aesthetic outcomes is possible not only by the material used but also by the self-organisation of the structure's optimisation. New fabrication techniques linked with topology optimising software change traditional load-bearing systems designing using timber and wood-based materials. Multi-objective optimisation research indicates that timber might be a comprehensive material based on various applications from low-tech to cutting-edge contemporary fabrication technologies. The article presents new tools and methods for the optimisation of structural elements. A case study based on interdisciplinary architectural and structural optimisation suggests the possible effective research-based design. Comparing contemporary buildings with wood load-bearing structures explains timber usage's diversity and characteristics in modern design.