Introduction: Leaving Against Medical Advice (LAMA) can cause a state of dilemma among the treating physician whether to continue the treatment or to de-escalate from the treatment. It can deteriorate the primary disease of the patient, leading to an increase rate of re-admission to the hospital, increased morbidity and mortality. This is a worldwide phenomenon and the prevalence of LAMA varies between various countries and between different region, religion, and the socioeconomic status of the patient in the same country.Methods: The hospital records from 1st December 2018 to 30th November 2019 of a tertiary care teaching hospital were studied. Patient demography, disease characteristics and length of ICU stay and the factors leading to LAMA were noted and statistically analysed.Results: During the study period, 14.5% of patients asked for LAMA. The mean age was 51.22 ± 22.39 years (range 8 months to 97 years) with Male predominance (n= 288, 62.60%) over Female (n= 172, 37.39%). Patients residing in rural areas were 56.08% (n=258) and 63.91% were financially dependent on others for their living. The mean length of stay in hospital was 3.02 ± 3.50 days while 30.86% of patients required mechanical ventilation. About 51.73% of patients taking LAMA were admitted from the Internal medicine department. Around 79.56% were Hindus, with 54.34% opting for LAMA due to financial restrain followed by poor prognosis (22.60 %).Conclusion: The large number of patients admitted in ICU opts out for LAMA. This necessitates formulation and implementation of strategies to reduce the prevalence of LAMA discharge so that patient gets the optimum level of care and the burden in the health care system is reduced

Background: Laparoscopic surgeries are commonly performed under general anesthesia using endotracheal intubation. Laryngoscopy and endotracheal intubation cause exaggerated hemodynamic response which may be detrimental to hypertensive patients and those with cardiac issues. I-gel, a second generation supraglottic airway device mitigates this effect and can be safely used under general anesthesia. Methods: This was a prospective comparative study consisting of 64 patients undergoing laparoscopic surgery. The patients were divided into endotracheal tube group and I-gel group, each group with 32 patients, which was done according to convenience sampling method.  Patient’s baseline heart rate, systolic, diastolic and mean arterial blood pressure was recorded. These parameters were recorded at one, three and five minutes of placement of airway device, after creating caboperitonium and after extubation which were compared statistically. Results: Exaggerated hemodynamic response was observed in endotracheal tube group after endotracheal intubation and immediately after extubation as compared to I-gel group which were more stable. However, both the group had similar hemodynamic response during carboperitonium. Conclusions: I-gel can be safely used in laparoscopic surgeries under general anesthesia and also lessens the hemodynamic response as compared to endotracheal tube during laryngoscopy and intubation.