Atherosclerotic Cardiovascular Disease (ACVD) is one of the leading causes of death throughout the world. ACVD is inflammatory and occurs due to the deposition of lipids in the arterial lumen. The increasing trend of ACVD can be attributed to the sedentary lifestyle and it is imperative to investigate the causes of ACVD and their prevention. The human gut hosts an enormous diversity of microbes. This enormous microbial community inhabiting the human gut are responsible for several conditions associated with ACVD and plays a crucial role in its progression. Different methods for studying gut microflora have been developed, which has led to the discovery of dysbiosis. Dysbiosis is the change in homeostasis of the microfloral community. Several external factors are responsible for the dysbiosis including diet, mode of delivery, age, sex, body mass index, host genetics, and antibiotic usage. Dysbiosis results in the release of altered amounts of some bioactive metabolites such as short-chain fatty acids (SCFA), bile acids, and trimethylamine-N-oxide (TMAO) which can be a contributing factor in the progression of atherosclerosis. This review will enlist the role of dysbiosis of gut microbiota in atherogenicity and their relevant applications in its prevention. With an adequate understanding of the process involved in gut microbiota dysbiosis, scientists worldwide can develop potential therapeutics for ACVD.

Mushrooms and algae have been consumed since ancient times because of their culinary and gastronomic attributes. Both are important dietary sources of bioactive compounds including essential minerals, vitamins, complete profile of amino acids and are valuable source of dietary fibres. They are low in calorie content because of negligible amount of fats and carbohydrates. Beyond the excellent nutrition profile of these superfoods, they also belong to the category of nutraceuticals which provide medicinal benefits along with meeting daily dietary requirements. Bioactive compounds present in them are an interest of research because of anti-cancerous, antimicrobial, antiviral, antioxidant, hypoglycemic and immunomodulatory activities. These microorganisms are easy to grow on varied substrates therefore cost effective and eco-friendly that gives a great advantage over synthetic super foods obtained from animal origin. The current review focusses on the nutritional and medicinal value with importance of mushrooms and algae as a super food. Review also discusses about the toxicity associated with mushrooms along with the current status in trends of production, cultivation and consumption of fungi and algae based foods in different countries and offers thoughts on course.