Background: The liver and kidney play a central role in metabolic and detoxification processes leads to structural degeneration of organs with aging, which may hamper the functional ability of these organs. Acharya charaka suggests to use drugs of vayasthapana mahakashaya in different combinations to prevent ageing. Guduchi (Tinospora cardifolia) and punarnava (Boerhavia diffusa) are two drugs chosen to evaluate the solitary and combined effect on structural and functional changes in liver and kidney of Wistar rat. Materials and Methods: After identification and phytochemical study of test drugs, the 32 healthy, male rats of 18 months will be divided into four different groups, with eight rats in each group. 1st to 4th group will receive distilled water, guduchi kwath, punarnava kwath, guduchi and punarnava kwath respectively for 30 consecutive days at the rate of 8.1ml/kg dose, orally. Before administration of control drug and test drug blood sample assessment will be done for LFT, KFT, and SOD level. The same investigation will be repeated after one month trial period. Then after 60 days,120 days and 180 days, two animals from each group will be sacrificed, organs such as liver and kidney will be extracted and preserved for histopathological study, and blood samples will be collected for investigation. The remaining animals will be returned to the animal house for their reuse. Expected Results: Guduchi and punarnava may provide strength to liver and kidney and thus helpful in delaying degenerative changes of organs.

Ayurveda is the life science. Its objects are to maintain the health of healthy individual and cure of diseases mainly contributed by Aahara, Nidra and Brahmacharya. Being supported by these three sub pillars of life, the body is endowed with strength and growth. Present era is full of competition, everyone is struggling for existence. Man is working hard for day and night, besides that mental stress, addiction of alcohol, tobacco leads to insufficient sleep. The disease Nidranash (Insomnia) is gradually increasing in society and has become one of the common problem. According to modern science, pharmacological treatment advice in this case shows various side effects. Through this study effort was taken up to find out nonpharmacologic therapy to cure this crippling disease. Aim of present study was to evaluate the effect of non pharmacological therapy Shirodhara in Nidranash. Study was conducted in 30 clinically diagnosed patient of Nidranash with help of symptoms of Nidranash and Sleep Efficiency Index (SEI). Procedure of Godugdha Shirodhara was carried out in three steps purvakarma, pradhankarma and paschatkarma with all precautions. On the basis of observed data, it was concluded that Godugdha Shirodhara has highly significant effect on Nidranash.

Ethics deal with the set of principles of right conduct. The four basic principles of bioethics - autonomy, beneficence, non-maleficence and justice are known as “principlism". Though these four principles are influenced by the western world; in the medical field they are adapted as universal ethics. Originally, Ayurveda, the Indian medical system, has strongly advocated ethical code of conduct for physicians, but does not get its due recognition till this date. Proposed article aims to compare universally accepted basic tenets of bioethics and ancient Ayurvedic ethics. For this purpose classical texts of Ayurveda and literature regarding principlism was collected and analyzed thoroughly. It was found that the essence of ethics is very well-defined and described in the fundamental texts of Ayurveda in the form of Sadvritta, Chatushpada, Yogya, Vaidyavritti and Aachara Rasayana. Hence, Ayurveda should be considered as a trailblazer in establishing the basic tenets of bioethics.

Ayurveda adapt comprehensive psychosomatic approach to maintain health and cure disease. According to basic concept pravar satva sara person is able to bear any kind of mental stress, strain and pain. Cancer is one of the disease where needs psychosomatic approach of treatment to improve quality of life, specially breast cancer in females patients. Thus with an objective to know the importance of satvasarata in prognosis of female breast cancer female, in relation with blood indices, study was carried out. 60 patients selected according to selection criteria. Assessment Satva sara was done with proforma provided by MUHS, Nashik. Blood indices Hb, TLC, platelets, Blood urea, serum creatinine, SGOT and total bilirubin were observed for three consequently fallow up, on the basis of data obtained; pravar satva sarata female patients show good response to treatment with minimal changes in their blood indices.

Ayurveda is Divine science due to its origin as well as its incredible potency in curing the diseases and pro-tecting the health of a healthy person. In the current era sedentary lifestyle, unbalanced diet, tense mental conditions, smoking, drinking alcohol have led to lifestyle disorders, causing a lot of complications that are difficult to remove. This results in the most common lifestyle disorders like hypertension, diabetes mellitus, arthritis, obesity, etc. Lifestyle disorders are a big problem for our society today. The onset of those disor-ders is insidious, they take years to develop, and once encountered, they are not easily cured. A healthy lifestyle is a valuable resource for reducing the incidence and impact of health problems, for recovery, for coping with life stressors, and for improving quality of life. At present, people are again getting attracted to, an ancient system of healing, Ayurveda as it rectifies disease along with, lifestyle originated consequences. In the management of lifestyle disorders, Ayurveda offers various regimens including Ahara (proper die-tary management), Dincharya (daily regimen) Ritucharya (seasonal regimen), Panchakarma (five detoxifi-cation and bio-purification therapies), Rasayana (rejuvenation) therapies and Sadvritta (moral). These are the basic tenets of Ayurveda. The inclusive utilization of all these treatment modalities has a great effect on lifestyle disorders. And hope to treat lifestyle disorders brighten with the broader approach of Ayurveda. This is an attempt to grab the attention of Ayurveda vaidya towards the unique basic tenets of Ayurveda explained by ancient Ayurvedacharya.