A new resource for studying structure property relationships is presented, namely a systematic database of 36 organic salt structures together with phase specific aqueous solubility data. The salts are derived from four M2+ cations (Mg2+, Ca2+, Sr2+, Ba2+) and nine substituted benzoate anions. The intrinsic solubility of the free acid is found to have a major contribution to make to salt solubility, but despite previous literature assertions, there appears to be little correlation of solubility with the polarity of the organic ions, with cation size, or with hydration state. Importantly, we also show that consideration of the array structure rather than just molecular considerations improves prediction of rank orders of solubility. Thus, three-dimensional intermolecular networks (here formed with hydrogen bonding, M−O−M and M−N−M interactions, and halide interactions) are found to have lower aqueous solubilities than lower dimensional networks.

Experiences such as loss and diminishing identity have previously been understood as a direct result of dementia, with little consideration of interpersonal influences. This review notes that people with dementia actively engage with others, whose responses can foster or undermine social well-being. This dynamic relational aspect may contribute to emerging understandings of social health in dementia.

One aspect of the NHS Long Term Plan is to establish a more comprehensive community-based mental health crisis response. NHS trusts have therefore looked to new services to help alleviate in-patient bed pressures. Intensive Outpatient Programmes (IOPs) have been previously used to help support people living with substance-misuse or eating disorders. More recently IOPs have been utilised to support people living with depression and anxiety. The Acute Community Service (ACS) was established as an IOP to support older adults in crisis by providing psychological, nursing, occupational, and physiotherapy interventions. Initial findings are consistent with previous research showing significant improvements in mood, levels of anxiety, and quality of life, with some service users being suitable for discharge to primary care. The ACS looks to build on these promising findings by working towards understanding the impact of the service on the frequency and length of in-patient admissions. Additionally, we would aim to understand the longer term impact of the ACS on service users and re-referrals rates.

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