Large congenital melanocytic nevi (> 20 cm in greatest diameter) are very rare and are seen in approximately 1 in 20,000 newborns. The major risk these patients face is the development of neurocutaneous melanosis or malignant melanoma. We report a rare case of large congenital melanocytic nevus with metastatic melanoma in a 40-year-old woman. In this case, though the primary was not established with certainty, on the basis of clinical course and radiological evaluation of various organs, we presume that the primary could be in the lung.

Breast lumps are very common in patients presenting to the outpatient department. Most of them are benign lesions and the malignant lesions are diagnosed with the help of FNAC and ultrasonography. Carcinoma breast is the second most common cancer after cancer cervix. FNAC is a safe, reliable, time saving and cost effective procedure useful in the diagnosis of carcinoma breast It helps the surgeon in planning the treatment, and thereby reducing the delay in treatment. The present study is done with the aim of studying the incidence of various breast lesions on FNAC and their Histopatlological correlation among rural polation of Vikarabad. Materials and Methods: This is a retrospective study carried out in in the Department of Pathology, MIMS, Vikarabad. 95 FNACs conducted in the department of Pathology from April 2019 to March 2020 were analysed. Of these 75 cases were subjected to histopathological examination. Results: Of the 95 cases studied by Fine needle aspiration cytology, 76 were Benign and 10 were malignant. In 4 cases the aspirate was unsatisfactory and 2 cases were diagnosed as atypical. 3 cases were diagnosed as suspicious of malignancy. 75 cases were removed by either excision biopsy or Modified radical mastectomy and evaluated by histopathological examination the age group of the patients ranged from 18 to 70 years. Of the 76 cases diagnosed as Benign by FNAC, two cases showed atypical ductal hyperplasia on histopathology Two cases diagnosed as atypical turned out to be fibrocystic disease with apocrine metaplasia. Three cases diagnosed as suspicious for malignancy were confirmed to be malignant lesions on histopathology. All the 10 cases diagnosed as malignant on FNAC were confirmed to be malignant on histopathology. Conclusion: FNAC is a useful tool to diagnose malignant lesions of the Breast and they aid the surgeon in differentiating benign and malignant lesions. They help in quick and effective management of malignant lesion of the breast and thereby reduce the mortality in these patients.

The occurrence of a ganglion cell containing pituitary adenoma is an uncommon entity. We report a rare case of a sellar mass of ganglion cell containing pituitary adenoma showing unusual demographic and radiologic features.