The aim of this study was to develop a process of extraction oxyresveratrol from Artocarpus lakoocha heartwood using a maceration method. The influences of types of solvent, a concentration of solvent, and time to extract on the yield of oxyresveratrol were studied. In addition, the antioxidant capacity of the extract was investigated. The quantitation of oxyresveratrol was measured by high-performance liquid chromatographyanalysis, and antioxidant activity was analyzed by 1,1'-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging assay. The results indicated that 70-percent ethanol solvent by volume for 6 hours could extract the optimum oxyresveratrol at 13.09 percent of the dry weight of Artocarpus lakoocha, and antioxidant efficiency had an IC 50 of 47.70 μg/ml.
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