This paper presents the recognition for WHO classification of acute lymphoblastic leukaemia (ALL) subtypes. The two ALL subtypes considered are T-lymphoblastic leukaemia (pre-T) and B-lymphoblastic leukaemia (pre-B). They exhibit various characteristics which make it difficult to distinguish between subtypes from their mature cells, lymphocytes. In a common approach, handcrafted features must be well designed for this complex domain-specific problem. With deep learning approach, handcrafted feature engineering can be eliminated because a deep learning method can automate this task through the multilayer architecture of a convolutional neural network (CNN). In this work, we implement a CNN classifier to explore the feasibility of deep learning approach to identify lymphocytes and ALL subtypes, and this approach is benchmarked against a dominant approach of support vector machines (SVMs) applying handcrafted feature engineering. Additionally, two traditional machine learning classifiers, multilayer perceptron (MLP), and random forest are also applied for the comparison. The experiments show that our CNN classifier delivers better performance to identify normal lymphocytes and pre-B cells. This shows a great potential for image classification with no requirement of multiple preprocessing steps from feature engineering.

Abstract-The performance of edge detection often relies on its ability to correctly determine the dissimilarities of connected pixels. For grayscale images, the dissimilarity of two pixels is estimated by a scalar difference of their intensities and for color images, this is done by using the vector difference (color distance) of the three-color components. The Euclidean distance in the RGB color space typically measures a color distance. However, the RGB space is not suitable for edge detection since its color components do not coincide with the information human perception uses to separate objects from backgrounds. In this paper, we propose a novel method for color edge detection by taking advantage of the HSV color space and the Mahalanobis distance. The HSV space models colors in a manner similar to human perception. The Mahalanobis distance independently considers the hue, saturation, and lightness and gives them different degrees of contribution for the measurement of color distances. Therefore, our method is robust against the change of lightness as compared to previous approaches. Furthermore, we will introduce a noise-resistant technique for determining image gradients. Various experiments on simulated and real-world images show that our approach outperforms several existing methods, especially when the images vary in lightness or are corrupted by noise.

No abstract

No abstract

SUMMARYA novel method is proposed to estimate the 3D relative positions of an articulated body from point correspondences in an uncalibrated monocular image sequence. It is based on a camera perspective model. Unlike previous approaches, our proposed method does not require camera parameters or a manual specification of the 3D pose at the first frame, nor does it require the assumption that at least one predefined segment in every frame is parallel to the image plane. Our work assumes a simpler assumption, for example, the actor stands vertically parallel to the image plane and not all of his/her joints lie on a plane parallel to the image plane in the first frame. Input into our algorithm consists of a topological skeleton model and 2D position data on the joints of a human actor. By geometric constraint of body parts in the skeleton model, 3D relative coordinates of the model are obtained. This reconstruction from 2D to 3D is an ill-posed problem due to non-uniqueness of solutions. Therefore, we introduced a technique based on the concept of multiple hypothesis tracking (MHT) with a motion-smoothness function between consecutive frames to automatically find the optimal solution for this ill-posed problem. Since reconstruction configurations are obtained from our closed-form equation, our technique is very efficient. Very accurate results were attained for both synthesized and real-world image sequences. We also compared our technique with both scaled-orthographic and existing perspective approaches. Our proposed method outperformed other approaches, especially in scenes with strong perspective effects and difficult poses. key words: perspective model, human skeleton, 3D tracking, MHT