Predicting defective software modules before testing is a useful operation that ensures that the time and cost of software testing can be reduced. In recent years, several models have been proposed for this purpose, most of which are built using deep learning-based methods. However, most of these models do not take full advantage of a source code as they ignore its tree structure or they focus only on a small part of a code. To investigate whether and to what extent information from this structure can be beneficial in predicting defective source code, we developed an end-to-end model based on a convolutional graph neural network (GCNN) for defect prediction, whose architecture can be adapted to the analyzed software, so that projects of different sizes can be processed with the same level of detail. The model processes the information of the nodes and edges from the abstract syntax tree (AST) of the source code of a software module and classifies the module as defective or not defective based on this information. Experiments on open source projects written in Java have shown that the proposed model performs significantly better than traditional defect prediction models in terms of AUC and F-score. Based on the F-scores of the existing state-of-the-art models, the model has shown comparable predictive capabilities for the analyzed projects.INDEX TERMS Software defect prediction, deep learning, graph neural network.

Gestational diabetes mellitus (GDM) is a common complication of pregnancy that adversely affects maternal and offspring health. A variety of risk factors, such as BMI and age, have been associated with increased risks of gestational diabetes. However, in many cases, gestational diabetes occurs in healthy nulliparous women with no obvious risk factors. Emerging data suggest that the tendency to develop gestational diabetes has genetic and environmental components. Here we develop a polygenic risk score for GDM and investigate relationships between its genetic architecture and genetically constructed risk factors and biomarkers. Our results demonstrate that the polygenic risk score can be used as an early screening tool that identifies women at higher risk of GDM before its onset allowing comprehensive monitoring and preventative programs to mitigate the risks.

No abstract

No abstract