Introduction: Management of distal end radius intraarticular fractures is difficult to manage and these fractures account for 10% of all fractures. Multiple treatment options ranging from conservative to internal fixation, of which volar plate fixation has emerged as an effective method of internal fixation in comparison with other fixed-angle locking plates as they ensure proper restoration of the articular surfaces and anatomical alignment. Materials and Methods: A hospital-based prospective study was conducted on 14 patients with distal end radius fractures admitted in our hospital from January 2019 to December 2019. Patients with distal end radius fractures treated with variable-angle locking plate were included and were followed-up minimum of 6 months. The results were analyzed based on radiological parameters and Mayo Wrist Score (MWS). Results: Of 14 patients, 11 were male patients and three were female patients. Seven patients had right-sided fracture whereas remaining seven patients had left-sided fractures. All 14 patients were treated with variable-angle locking plate. Among 14 patients, 12 patients achieved union by 12 weeks, only two patients achieved union by 24 weeks. Ten patients had excellent results while four patients had a good outcome based on MWS. All patients in our study had painless union without any complications. Conclusion: The use of variable-angle locking plates in distal end radius fractures helps to maintain perfect anatomical reduction, early mobilization, and better postoperative outcome.