This paper introduces two-dimensional loading time-dependent vehicle routing problem and proposes a biobjective mathematical model. This problem assesses the process of distributing the rectangular-shaped demanded items over an urban environment; it does not, however, allow items to be loaded on top of each other. In addition to the above assumptions, the presented model also satisfies the first-in-first-out property in the timedependent vehicle routing problem. Given the NP-hard nature of the problem, a method called elitist nondominated sorting local search is developed to obtain its solutions. To evaluate the performance of the proposed algorithm, the solutions of this algorithm for small-scale problem instances are compared with the results of an exact method. For the medium-scale problem instances, results of NSGA-II and SPEA2 are used as the basis of comparison. The computational results demonstrate the good performance of the proposed method.