Background: Beyond the current pandemic of COVID-19 disease, development and subsequently global access of vaccines against SARS-CoV-2 is vital. However, concern about vaccine hesitancy (delay in acceptance or refusal of vaccination despite availability of vaccination services) is a growing issue. With limited literature, this study aims to explore vaccine hesitancy for COVID-19 disease among health care workers.Methods: We conducted a cross-sectional anonymous online survey on heath care workers of medical college, Agra from 1 to 15 January 2021. Survey consisted of questions on demographic background, health status, and willingness for vaccination, reasons for unwillingness and items related to information about COVID-19 vaccination.Results: The study received responses from 400 health care workers. In present study, 233 (58.25%) responded that they are very likely to get COVID-19 vaccine (vaccine acceptance). 33.50% of HCWs were uncertain about being vaccinated (vaccine hesitant) and 8.25% HCWs reported that they are very unlikely to get vaccinated (vaccine resistant). Females were less willing for vaccination and significant gender wise difference was found. Majority of participants cited side effects (56%) and fast moving clinical trials (45%) as reasons for not going for vaccination. In context of COVID appropriate behavior, 93%, 77% and 70% responded that they will wear mask, practice social distancing and avoid social gatherings respectively even after vaccination.Conclusions: Our study finds that COVID-19 vaccine hesitancy and resistance in HCWs is 41.75%. Governments, public health officials and advocacy groups must be prepared to address hesitancy and build vaccine literacy so that the public will accept vaccine.

Introduction Last year in December 2019 a new disease of corona virus, responsible for new cases of pneumonia was detected in Wuhan City of China. The outbreak of the disease has put an impact at all levels of education including professional institutes. It has left the institutes with no other option than to shift the entire curriculum to online formats which include online teaching along with self directed learning. So a study was planned to assess the knowledge and attitude of 100 first year MBBS students of Ameer ud din Medical College towards self directed learning about Corona virus disease pandemic. Methodology. This cross sectional study was done on 100 first year MBBS students of Ameer ud din Medical College in the first week of April. They were first given a questionnaire having thirteen questions about COVID-19 symptoms, spread, mode of transmission and prevention, and then after few days  were given an assignment which had questions related to response of immune system towards SARS CoV2. Result Out of 100 students80% of the students responded to questionnaire. Out of this 80%, 40 % of the students showed outstanding performance with 100% correct answers, and 40% of students had maximum of four wrong answers. Response rate of the assignments was 95%, with outstanding performance of A+, 5% and A grade by  41% students, 38 % had B and 11 % of the students got C grade. Conclusion Majority of the first year medical students  had adequate knowledge about COVID -19 and challenge of self-directed learning even at this level can make them show outstanding performance.