Deep Convolutional Neural Networks (CNNs) have recently demonstrated impressive results in electroencephalogram (EEG) decoding for several Brain-Computer Interface (BCI) paradigms, including Motor-Imagery (MI). However, neurophysiological processes underpinning EEG signals vary across subjects causing covariate shifts in data distributions and hence hindering the generalization of deep models across subjects. In this paper, we aim to address the challenge of inter-subject variability in MI. To this end, we employ causal reasoning to characterize all possible distribution shifts in the MI task and propose a dynamic convolution framework to account for shifts caused by the inter-subject variability. Using publicly available MI datasets, we demonstrate improved generalization performance (up to 5%) across subjects in various MI tasks for four well-established deep architectures.

Transfer learning and meta-learning offer some of the most promising avenues to unlock the scalability of healthcare and consumer technologies driven by biosignal data. This is because current methods cannot generalise well across human subjects' data and handle learning from different heterogeneously collected data sets, thus limiting the scale of training data. On the other side, developments in transfer learning would benefit significantly from a real-world benchmark with immediate practical application. Therefore, we pick electroencephalography (EEG) as an exemplar for what makes biosignal machine learning hard. We design two transfer learning challenges around diagnostics and Brain-Computer-Interfacing (BCI), that have to be solved in the face of low signal-to-noise ratios, major variability among subjects, differences in the data recording sessions and techniques, and even between the specific BCI tasks recorded in the dataset. Task 1 is centred on the field of medical diagnostics, addressing automatic sleep stage annotation across subjects. Task 2 is centred on Brain-Computer Interfacing (BCI), addressing motor imagery decoding across both subjects and data sets. The BEETL competition with its over 30 competing teams and its 3 winning entries brought attention to the potential of deep transfer learning and combinations of set theory and conventional machine learning techniques to overcome the challenges. The results set a new state-of-the-art for the real-world BEETL benchmark.

Building subject-independent deep learning models for EEG decoding faces the challenge of strong covariate-shift across different datasets, subjects and recording sessions. Our approach to address this difficulty is to explicitly align feature distributions at various layers of the deep learning model, using both simple statistical techniques as well as trainable methods with more representational capacity. This follows in a similar vein as covariance-based alignment methods [1], often used in a Riemannian manifold context [2].The methodology proposed herein won first place in the 2021 Benchmarks in EEG Transfer Learning (BEETL) competition 1 , hosted at the NeurIPS conference 2 . The first task of the competition consisted of sleep stage classification, which required the transfer of models trained on younger subjects to perform inference on multiple subjects of older age groups without personalized calibration data, requiring subject-independent models. The second task required to transfer models trained on the subjects of one or more source motor imagery datasets to perform inference on two target datasets, providing a small set of personalized calibration data for multiple test subjects.