Tendons are unique forms of connective tissue aiming to transmit the mechanical force of muscle contraction to the bones. Tendon injury may be due to direct trauma or might be secondary to overuse injury and age-related degeneration, leading to inflammation, weakening and subsequent rupture. Current traditional treatment strategies focus on pain relief, reduction of the inflammation and functional restoration. Tendon repair surgery can be performed in people with tendon injuries to restore the tendon’s function, with re-rupture being the main potential complication. Novel therapeutic approaches that address the underlying pathology of the disease is warranted. Scaffolds represent a promising solution to the challenges associated with tendon tissue engineering. The ideal scaffold for tendon tissue engineering needs to exhibit physiologically relevant mechanical properties and to facilitate functional graft integration by promoting the regeneration of the native tissue.
A popular water pipe system used in many countries is one formed by prestressed cylindrical concrete pipes (PCCPs) formed by identical precast moduli joined together in situ. This technology was and still is quite popular in many water supply systems internationally. This technology was mainly selected at the time due to its cost-based comparative advantage. However, over the years, numerous incidents of structural failures have been reported for this type of pipeline, causing, in some cases, serious disruption of the water supply. This study summarizes the results of an experimental investigation on ten (10) PCCP specimens taken from an existing water pipeline with the objective of investigating their bearing capacity under either three-edge bending or internal hydraulic pressure loads. Moreover, there is a need to check the capability of specific retrofitting/strengthening schemes to upgrade this bearing capacity and thus enhance the operational period. Provided that the prestressing wires are fully active according to design specifications, the original specimen performed satisfactorily for the set internal hydraulic pressure limit of 8.5 bar. Specimens retrofitted with either internal or external CFRP or RC jacketing performed satisfactorily for internal hydraulic pressure levels well above this 8.5 bar limit. A critical factor is, as expected, the loss of prestress.
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