Six patients (4 with post-operative radiotherapy, 2 without) were formally assessed by a speech and language therapist 12 months post-operatively. Patient-reported quality of life (QOL) was simultaneously measured. Patients treated with post-operative radiotherapy had lower overall speech comprehensibility scores, poorer swallowing function in puree and solid foods and lower overall QOL.

Clear cell odontogenic carcinoma (CCOC) is a low-grade odontogenic carcinoma showing cells with clear cytoplasm arranged in sheets and islands. Most of the CCOC typically present as swelling in anterior region of the mandible in elderly female patients. Radiographically, it exhibits ill-defined unilocular or multilocular radiolucency with tendency to cause bone destruction and tooth resorption. The present case report discusses the clinical, histological and immunohistochemical characteristics of a CCOC which was treated with surgery and adjuvant radiation therapy.

Cancer of the oral cavity is one of the most common cancers all over the world. Oral cancer and its treatment impacts on patients’ Quality of Life (QOL). The purpose of the present study was to assess oral cancer patients’ QOL after the completion of surgical therapy, and to investigate factors affecting it. This was a prospective cohort study, conducted at the Department of Oral & Maxillofacial Surgery, of a large general public hospital in Northern Greece. The sample consisted of 135 consecutive eligible cancer patients. Three distinct questionnaires were used. The first one included questions regarding the participants’ demographic characteristics and relevant clinical information. The second comprised the European Organization for Research and Treatment core module (EORTC QLQ-C30) and its head and neck module EORTC QLQ-H&N35. The third was the Functional Assessment of Cancer Therapy–General (FACT-G) assessment of quality of life. We also included the physician-completed Karnofsky scale to assess the functional status of the participants. We found that location of the tumor affects QOL and specifically social contact (H = 17.89, p = 0.001), on the first assessment, and nutritional supplements (H = 22.49, p = 0.000), on the fourth assessment. QOL in patients deteriorates immediately after treatment but significantly improves over time. Health care professionals should take into account these results and arrange care plans in order to find ways to increase patients’ QOL.