This article presents a clinical case demonstrating the correction treatment of the lower extremities in a patient with Issacs syndrome, as well as the results of ankle surgery and successful post-surgery rehabilitation. The high efficiency of surgery as a treatment method was confirmed.

Abstract. Relevance. Angiofibroma (angiomyofibroblastoma) is a rare soft tissue benign tumor. There are no descriptions of foot angiofibrom observations in the Russian specialized literature, which makes publications of this kind of materials relevant. The aim of the study was to analyze the experience of treatment of large locally advanced angiofibroma of the foot. Material and methods of research. A 17-year-old patient, according to ultrasound scanning and MRI, had a significant soft-tissue encapsulated tumor of the right foot. On 06.09.2018, a tumor removal operation was performed from three anatomical approaches - medial, posterior and plantolateral - with the maximum possible compliance with the principles of oncosurgery. Results and discussion. There were no complications, the wound healed by primary tension. Conclusion of histological examination of the extracted fragments of the tumor – angiofibroma of the foot. There is no data on tumor recurrence at the moment – more than three years after surgery. Conclusion. Summing up the data of various authors and our own experience, it can be argued that angiofibroma (angiomyofibroblastoma) is a benign slowly expansively growing tumor, more often localized in the area of the external genitalia mainly in women, but also affecting the foot. An exhaustive preoperative examination using ultrasound scanning and MRI, careful preoperative planning based on the principles of oncosurgery, taking into account the complex topographic and anatomical features of the foot and the full implementation of this plan in a specialized hospital allows you to avoid complications and achieve a long relapse-free period in the surgical treatment of large locally advanced angiofibroma of the foot.

Abstract. Among all neoplasms of the skeleton, enchondroma is 12%, among benign bone neoplasms - 10 - 27%. Frequent localization of enchondroma - short tubular bones of the hands and feet. It is possible to transform an enchondroma of the foot into a chondrosarcoma. Clinical guidelines with a sufficiently substantiated clear diagnostic and therapeutic tactics for enchondromas and chondrosarcomas of the first degree have not been developed to date. The aim of the study was to evaluate the effectiveness of intralesional resection with adjuvant chemical ablation in the treatment of enchondroma and chondrosarcoma of the first degree of the toe on a clinical example. Materials and Methods: A 64-year-old female patient with long-term symptoms on the side of the 5th toe of the right foot and a significant progression of these symptoms over the past three months underwent removal of the soft tissue component of the tumor of this finger, intralesional resection of its distal phalanx, and adjuvant chemical ablation. Healing by primary intention. According to the histological examination, the excised tissue corresponded to an enchondroma with areas of degeneration into grade I chondrosarcoma. Results: The patient was followed up for two years after the operation. There was no tumor recurrence. The patient did not experience pain, difficulty walking, considered herself practically healthy. Conclusion: the above clinical observation confirms that intralesional resection with adjuvant chemical ablation in the treatment of enchondroma and chondrosarcoma of the first degree of the foot allows to avoid relapses and ensure good function in the near and long term.