Background: Vescica ileala padovana (VIP) is a technique of bladder substitution following radical cystectomy with the advantage of resulting in a shape that anatomically resembles the real bladder. We studied whether the VIP neobladder is a viable alternative following cystectomy. Patients and Methods: Forty-five patients with muscle invasive bladder cancer were treated with radical cystectomy and VIP neobladder formation. Both perioperative and postoperative complications together with short- and long-term results were discussed. Results: In the early postoperative period there was one patient (2.2%) who developed ileus and one death (2.2%) due to a massive pulmonary embolism. During follow-up, 2 patients (4.4%) presented with hernias and 1 died from metastatic disease (2.2%), 3 patients (6.6%) developed ureteroileal strictures and 1 developed (2.2%) urethroileal stenosis. During follow-up, maximum capacity increased (540 ± 89 vs. 590 ± 54 ml, p = 0.014) while Qmax and end-filling pressure decreased (18 ± 2 vs. 14 ± 4 ml/s, p = 0.002 and 22 ± 3 vs. 15 ± 6 cm H2O, p = 0.012). The number of intrinsic contractions remained stable (4 ± 1 vs. 5 ± 1, p = 0.066). Daytime continence between the 3rd and the 36th month was stable (40 vs. 39 pts, 88.8 vs. 86.6%, p = 0.09). Twenty-six patients were continent during the night and this number increased to 30 patients (57.8 vs. 66.7%, p = 0.013). Conclusions: VIP has a favorable outcome and can be used for bladder orthotopic substitution following cystectomy.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.