Secondary localization of urothelial carcinoma after cystectomy or total cystoprostatectomy (CPT) on the penis (metastasis) is rare, representing 1 to 8%. Occurring within 18 months of the diagnosis of the primary lesion in about 65% according to the literature. The prognosis is often poor with survival rarely exceeding 20 months. The treatment of cavernous metastases of the penis is multidisciplinary, essentially based on surgery (emasculation or penectomy) and chemotherapy, which provide the best results in terms of overall survival. The authors report a case of metastasis, cavernous location of the penis after cystoprostatectomy in 2016 for high-grade urothelial carcinoma of the bladder, whose anatomy-pathology of the surgical specimen is classified pT3a. The patient underwent emasculation (penectomy plus bilateral total orchiepidymectomy involving the entire scrotum). The authors also discuss the diagnostic, therapeutic and prognostic problems that this secondary location poses.
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