The method or process of delivering a pharmaceutical ingredient to create a therapeutic effect in people or animals is referred to as drug delivery. Nasal and pulmonary routes of medication administration are becoming increasingly important in the treatment of human illnesses. These methods, especially for peptide and protein therapies, provide potential alternatives to parenteral drug administration. Several medication delivery methods have been developed for this purpose and are being tested for nasal and pulmonary delivery. Chitosan, Alginate, vanilline oxalate, zinc oxalate, cellulose, polymeric micelles, Gliadin, and phospholipid are examples of these. Multidrug resistance, a key issue in chemotherapy, can be reversed with these nanoparticles. Surgery, chemotherapy, immunotherapy, and radiation are all well-established treatments used in cancer treatment. A nanoparticle has emerged as a potential method for the targeted delivery of medicines used to treat certain illnesses. Keywords: Nasal Drug Delivery, Pulmonary Drug Delivery, Nanoparticles