No abstract

person-years). Of 12,675 CT/NG treatment episodes, 3,221 (25.4%) were empiric therapy in asymptomatic contacts, of which 2,076 (64.4%) were later confirmed to be negative for both infections. Conclusions Antibiotic use and overtreatment are high in a population at elevated risk for antibiotic resistant infections; these results should prompt reexamination of indications for empiric antibiotic treatment, particularly among contacts to bacterial STIs, and the effects of empiric STI treatment on antimicrobial resistance.