The infection control knowledge among the nurses was fairly good; however, there is still a wide scope of improvement with regular educational programs and in-house training.

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Colobomatous cyst of the orbit is a rare malformation associated with microphthalmic globe or asymmetrically large globe. Usually, it appears since birth without any sex predilection and can affect one globe or rarely both the globes. A coloboma is a gap or defect in the globe resulting from the failure of the choroidal fissure to close. A coloboma may be an isolated finding or a part of a complex syndrome. Orbital cystic lesions in childhood differ in their pathology and management. MRI & CT scan can demonstrate the anatomic relationship of the cyst to the globe, prior to surgical intervention as well as any associated developmental anomalies of the brain. We report an 11 year male child with bilateral retrobulbar optic nerve Colobomatous cyst, presenting with diminution of vision, evaluated clinically and radiologically by CT & MRI.

The increasing prevalence of multi-drug resistant Gram-negative pathogens in intensive care units has led to the revival of colistin. Colistin had gone into disrepute in early 1970s because of numerous reports of adverse renal and neurological effects. The renewed interest in colistin has also revived the discussion about its toxicity. The neurotoxicity reported in literature is usually with higher doses of colistin. We present a case report of seizures in a critically ill-patient, possibly with low dose colistin. A 47-year-old hypertensive female with chronic kidney disease-5 with sepsis on colistimethate sodium 1 million units (80 mg), intravenous once daily, developed paresthesias and seizures on 12th day of therapy, which were subsequently controlled after withdrawl of the drug. To conclude, colistin should be considered as a cause of convulsions in critically ill-patients with renal failure, even when given in low dose and patient receiving intermittent hemodialysis, when other obvious causes have been ruled out. When possible, cessation of therapy may be considered.