Objective: The objective of the study was to assess the level of knowledge and awareness about metabolic syndrome (Met S) and its components among the 1st year physiotherapy students and also the difference in the level of knowledge and awareness among male and female students. Methods: A self-administered structured questionnaire consisting of 90 questions about components of Met S was distributed among 38 students studying 1st year physiotherapy at Apollo College of Physiotherapy, Hyderabad, after obtaining a written consent from them. The data extracted were tabulated, statistically analyzed and results were obtained. Results: Physiotherapy students have good knowledge about types and causes of diabetes and poor knowledge about symptoms, biochemical process, and complications of Met S. They expressed poor knowledge to understand the link between hypertension and pregnancy. They could understand the role of hereditary factors only in diabetes but not in other components. Conclusion: Met S is a common disorder in the society; therefore, the awareness should be raised among the student population and as paramedics, it is their responsibility to communicate with the public about the risk factors and complications associated with it and counsel them to adopt a healthy lifestyle to protect themselves from the complications.

Context: Overt hypothyroidism is the most common endocrine disorder associated with a decrease in 3,5,3’-triiodothyronine and 3,5,3’,5’-tetraiodothyronine levels and increase in thyroid-stimulating hormone (TSH) levels. Thyroid hormones (THs) regulate all major metabolic pathways. THs play an important role in the synthesis, metabolism, and transport of lipids. Thyroid failure is associated with various biochemical and molecular alterations. Hypothyroidism is the common cause of secondary dyslipidemia as well as cardiovascular risk.Objective: The present review focuses on alterations in lipid metabolism associated with hypothyroidism leading to cardiovascular risk.Methods: The data source is from PUBMED, Google Scholar, and EMBASE. The study is a part of our previous research in studying the variations in lipid profile and transaminases in overt hypothyroidism.Result: The serum total cholesterol, low-density lipoprotein cholesterol (LDL-C), apolipoprotein B (apo B), lipoprotein (a) (Lp[a]), and triglycerides are elevated in individuals with overt hypothyroidism. In addition, it was also observed that the endothelial dysfunction, normal/depressed systolic function, left ventricular diastolic dysfunction at rest, as well as systolic and diastolic dysfunction on effort was observed in hypothyroidism.Conclusion: THs play an important role in the regulation of lipid metabolism. Hypothyroidism is also linked with altered hemodynamics. The atherogenic lipid profile along with other predisposing factors may contribute to the coronary artery disease.