As the population of older adults increases, healthy aging has become a global public health issue. Physical activity can help older adults reclaim or maintain a healthy aging process. The purpose of this paper is to investigate the relationship between physical activity, physical performance, quality of life and cognition in non-frail adults aged 65 and older. English articles in peer-reviewed journals about healthy, non-frail adults aged 65 and older were included in the present review. Additionally, articles were obtained from reviewing the reference lists of the aforementioned articles. Research proves an overwhelmingly positive correlation between physical activity and the reduction of preventable chronic illnesses, lower healthcare costs, improved cognition, improved muscle function, decreased fear of falling, and thereby, inevitably, an increased self-perceived quality of life. There is research evidence on healthy aging and the effect of physical activity, which could be of importance in a public health perspective.