Background:A prospective analysis was carried out over a 1-year period to assess gloves used during 100 major and 100 minor oral surgical procedures to test for efficacy of double gloving in oral surgical procedures.Purpose:The purpose of this study was to assess the efficacy of double gloving technique in preventing cross infection in both major and minor oral surgical procedures.Materials and Methods:Gloves used during 100 major and 100 minor oral surgical procedures were analyzed to check for glove perforations and skin punctures. 100 sterile gloves were tested as control.Statistical Analysis Used:Chi-square test was used to determine whether there was any difference between the expected and observed values in various categories.Results:A higher number of glove perforations was seen in minor oral surgical procedures compared with major surgeries, dominant hand compared with the nondominant, outer gloves compared with the inner, in procedures which took a longer duration of time to complete, in procedures involving wiring and in the index finger followed by the thumb and the palm.Conclusion:Double gloving technique using sterile gloves can be used as an effective means of infection control for all major and minor surgical procedures, especially high-risk procedures involving patients who maybe suffering from or carriers of blood-borne infections.

T ilapia hepcidin (TH), an antimicrobial peptide (AMP) derived from tilapia (Oreochromis mossambicus) forms an important component of the fish innate immune defense. 1 However, the functionality of TH is not just limited to its antimicrobial actions, significant applications in cancer research remain an area to be explored. Antimicrobial peptides derived from fish and shrimp demonstrated anticancer activities in addition to their previously discovered antimicrobial action. Three hepcidin-like AMPs can be isolated from tilapia, namely TH1-5, TH2-2, and TH2-3. Of these, TH1-5 and TH2-3 have shown potent antitumor activity. 2 The AMPs from fish exhibit numerous activities that make them promising candidates in cancer therapeutics. The antineoplastic effects of TH are summarized in Flowchart 1. Tilapia hepcidin causes inhibition of tumor cell proliferation. 3 The growth-inhibiting the potential of TH2-3 and TH1-5 is documented in the in vitro studies by Chen et al. 3 and Chang et al. 2 The antineoplastic effect was first shown on human hepatic fibrosarcoma cells. 3 They are also known to prevent tumor invasion and metastasis by affecting cancer cell motility. 4 This characteristic is supposedly due to electrostatic interactions among TH-treated cancer cells, which are not favored due to the neutral charge conferred on healthy cells by zwitterionic nature of their major membrane components such as phosphatidylethanolamine (PE), phosphatidylcholine (PC), and sphingomyelin (SM), and are therefore less attractive to TH2-3 and

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