We report the first, to the best of our knowledge, hand-in-hand collaboration between human rights activists and machine learners, leveraging crowd-sourcing to study online abuse against women on Twitter. On a technical front, we carefully curate an unbiased yet low-variance dataset of labeled tweets, analyze it to account for the variability of abuse perception, and establish baselines, preparing it for release to community research efforts. On a social impact front, this study provides the technical backbone for a media campaign aimed at raising public and deciders' awareness and elevating the standards expected from social media companies.

A b s t r a c tAim: The aim was to assess the impact of impaired renal function on myocardial tissue reperfusion in patients with ST-segment elevation myocardial infarction (STEMI) treated with primary percutaneous coronary intervention (pPCI).Material and methods: Impaired renal function was diagnosed at admission based on abnormal serum creatinine level (> 106 μmol/l). Patients with anterior STEMI and maximal single-lead ST-elevation (maxSTPost) exceeding 2 mm up to 90 min post-procedure, as well as patients with inferior STEMI and maxSTPost > 1 mm, were considered to have failed tissue reperfusion. The incidence of death or heart failure (NYHA class > 2) was prospectively assessed over a subsequent 12-month period.Results: Primary PCI and maxSTPost measurements were performed in 200 out of 208 consecutive patients (63.0 ±12.1 years, 67.5% males) treated between October 2007 and September 2008. Patients with impaired renal function (12.5%) died or developed heart failure more often when compared to the remaining individuals (56.0% vs. 16.0%, p < 0.001, respectively). Patients with failed reperfusion (15.5%) had higher incidence of one-year mortality and heart failure (35.5% vs. 18.3%, p = 0.032, respectively). Failed tissue reperfusion was 2.5 times more frequent among patients with impaired renal function, despite a relatively high rate of final TIMI 3 flow as compared to the remaining subjects (32.0% vs. 13.1%, p = 0.022 and 84.0% vs. 92.6%, p = 0.239, respectively). Impaired renal function and failed reperfusion were independent predictors of death or heart failure (odds ratio (OR) = 4.38, 95% confidence interval (CI) 1.34-14.28, p = 0.014, and OR = 3.34, 95% CI 1.12-9.88, p = 0.029, respectively). Impaired renal function was a risk factor for failed tissue reperfusion (OR = 2.98, 95% CI 1.03-8.68, p = 0.044).Conclusions: Impaired renal function in patients with STEMI treated with primary PCI is related to the risk for failed myocardial tissue reperfusion, leading in consequence to higher one-year mortality and heart failure.Key words: impaired renal function, myocardial tissue reperfusion, ST-segment elevation resolution S t r e s z c z e n i e Cel: Ocena wpływu upośledzonej funkcji nerek, rozpoznawanej w chwili przyjęcia do szpitala, na skuteczność reperfuzji tkankowej u chorych leczonych pierwotną angioplastyką wieńcową (primary percutaneous coronary intervention -pPCI) z powodu zawału serca z przetrwałym uniesieniem odcinka ST (ST-segment elevation myocardial infarction -STEMI).Materiał i metody: Upośledzoną funkcję nerek rozpoznawano, gdy stężenie kreatyniny było większe od normy (> 106 μmol/l). W czasie do 90 min od pPCI wykonywano 12-odprowadzeniowe badanie elektrokardiograficzne (EKG) i identyfikowano pojedyncze odprowadzenie z najwyższym uniesieniem odcinka ST (maxSTPost). Chorych ze STEMI ściany przedniej i wartością maxSTPost > 2 mm i chorych z zawałem ściany dolnej i wartością maxSTPost > 1 mm zakwalifikowano do grupy z nieskuteczną reperfuzją tkankową. Przeprowadzono prospektywną ocenę kliniczn...