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Introduction: Argyria is a rare condition caused by the body's over--exposure to silver compounds marked by blue-gray discoloration of the skin, mucous membranes, nails and internal organs. Case report: A 55-year-old man was referred to the dermatology clinic for diagnosing melanoderma present for about 5 years. Physical examination revealed a bluish-gray discoloration of the skin with highest intensity in the head and neck area. The patient had a history of an untreated delusional syndrome. He reported that he had consumed a colloid silver solution for several years as a method for self-treatment for viral warts. The presence of silver deposits was confirmed in the histological examination. Conclusions:The disease should be included in the differential diagnosis of abnormalities in skin color. The diagnosis for argyria is based on a medical history with clinical assessment for the skin in combination with the results of histological examination.

Acquired lymphangioma, also called acquired cutaneous lymphangiectasia or secondary lymphangioma, is a relatively rare and benign tumour consisting of dilated superficial lymphatic vessels. We present 50-year-old patient diagnosed with acquired lymphangioma of the vulva and discuss the diagnostic methods of the disease, including dermoscopy.

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Introduction:Acute infectious purpura fulminans is a rare life-threatening complication of sepsis, which rapidly progresses to acute circulatory failure due to intravascular thrombosis and extensive haemorrhagic purpura associated with disseminated intravascular coagulation and multiple organ failure. Case report: A 43-year-old man reported to the emergency room because of dyspnoea following traumatic splenectomy. On admission, the patient reported malaise, fever and chills. The incident happened within a few hours to the development of septic shock. A dermatological examination revealed bleeding spots that did not blanch under pressure, localized mainly on the face and genitals. Empirical antibiotic therapy with vancomycin, cefotaxime and metronidazole was initiated, and then the antibiotic therapy was changed to ceftriaxone. There was a rapid progression that required an amputation of the lower legs. Conclusions: Acute infectious purpura fulminans is a life-threatening disease that requires intensive treatment, but early cutaneous manifestations may facilitate diagnosis and appropriate management.