Syzygium cumini, also known as Jamun, Jambul, or Indian blackberry, is a species of tree native to the Indian subcontinent. A comprehensive literature review shows that Jamun can be considered one of the most versatile herbal medicines with anti-diabetic, anti-oxidant, anti-inflammatory, and other properties. This review aims to investigate and understand the previous research on Jamun, including its pharmacognosy and pharmacological history, to confirm its potential to treat a variety of illnesses. The study also examined the current pharmaceutical formulations available in the market to understand the potential for developing medications from the components of Jamun. To comprehend the available studies, the analytical backdrop is also reviewed. Despite being the focus of many research studies, there are still many unanswered questions regarding Jamun. Therefore, the best formulations or products may be produced in these sectors, possibly through nutraceuticals, to support improved pharmacological aspects or health promotion. This review will help identify unexplored areas where specific tasks related to Jamun can be done.
Any product generated from food sources that offer additional health advantages over and above the essential nutritional content present in foods is referred to as a nutraceutical under the broad umbrella term. The catechins in Camellia sinensis (Theaceae) namely (-)-epicatechin, (-)-epicatechin-3-gallate, (-)-epigallocatechin, and (-)-epigallocatechin-3-gallate (EGCG), which can be used as nutraceuticals in food or as a component of food items has been discussed. Catechins being polyphenols and antioxidants are found to have a wide range of therapeutic application like weight loss, anticancer, anti-inflammatory, and a few more therapeutic applications, through various mechanisms like stimulating AMP-activated protein kinase, enhanced apoptosis, decreased expression of interleukin (IL)-6 and IL-8. The most recent method for extracting catechins include combining the extraction processing of PEF or IPL with Subcritical water extraction. Food additives have been mixed with green tea extracts to develop a desired formulation like chewing gum and capsule. As green tea catechins are a beneficial phytoconstituents to improve overall health, its prospects include formulation of a gelatin gummy formulation which will improve its palatability by masking the bitter taste. Gelatin gummy formulation can be carried conveniently and will provide easy access to the consumer as compared to green tea. Furthermore, we found a scope to develop an analytical method for EGCG and carry out its validation by HPLC which will be more reliable and cost-efficient in comparison to the existing UHPLC methods for EGCG.
The current article consists of a review and literature about the use of the drug Amitriptyline Hcl as an antipsychotic, antidepressant drug along with its analytical features.Here we have also discussed about the analytical methods that can be carried out such as spectroscopy, chromatography etc. Analytical techniques can be roughly divided between classical and instrumental techniques. Volumetry (titrimetric), gravimetry, gasometer, and other antiquated techniques are examples of the former classical techniques. Spectroscopic techniques (UV-Visible, FS, AS, IR, NMR, etc.). Electrophoreticmethods, Chromatographic methods (CC, TLC, HPTLC, HPLC, GC, etc.), and other instrumental methods. An overview of the analytical techniques used to analyse the drug amitriptyline is provided in this publication. This article will help to gain deep knowledge and previous work done Amitriptyline HCL.The article also provide information about the forced degradation studies and procedure to perform degradation studies according to ICH guidelines.
The well-known tropical tree Psidium guajava, also known as the guava, is widely farmed for its fruit. This article consists of literature about various analytical techniques like TLC, UV spectrophotometry, HPLC, and HPTLC that could be used to analyze the Guava plant. The HPLC analysis of Quercetin isolated from the leaves of the guava plant uses a 4 x 125 mm Hypersil ODS column with a mobile phase of 0.5 percent ortho-phosphoric acid in water and methanol at a flow rate of 1ml/min. The column wash times are 20 min and 18 min, respectively. 250C is the temperature in the column. Silica gel 60F 254 pre-coated plates (10x10 cm) were used with toluene: acetone: formic acid (38:10:5) as the solvent system for HPTLC analysis of quercetin obtained from the tender leaves of guava. The λ max was observed in the U.V. spectrum of the isolated compound (quercetin) on three standard wavelengths: 212 nm, 256 nm, and 372 nm. An effort can be made to produce a new analytical method that will be cost-effective and time-saving.
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