Sarcopenic dysphagia is defined as difficulty in swallowing due to sarcopenia, which may be related to weakness of the tongue muscles. This meta-analysis aimed to explore the association between tongue strength and sarcopenia and to determine whether tongue strength measurement could be a specific indicator of sarcopenic dysphagia. We conducted a systematic search of electronic databases from their inception to February 2021 for clinical studies that investigated tongue strength in participants with and without sarcopenia. The primary outcome was the weighted mean difference (WMD) and standardized mean difference (SMD) of tongue pressure between the different groups. The secondary outcome was the correlation of tongue pressure with the subcomponents that defined sarcopenia. Ten studies that involved 1,513 participants were included in the meta-analysis. Compared with those without sarcopenia, patients with sarcopenia had significantly less tongue pressure, with a WMD of −4.353 kPa (95% CI, −7.257 to −1.450) and an SMD of −0.581 (95% CI, −0.715 to −0.446). There was no significant difference in tongue pressure between patients with sarcopenic dysphagia and those with non-sarcopenic dysphagia, with a WMD of −1.262 kPa (95% CI, −8.442 to 5.918) and an SMD of −0.187 (95% CI, −1.059 to 0.686). Significant positive associations were identified between tongue pressure and grip strength and between tongue pressure and gait speed, with correlation coefficients of 0.396 (95% CI, 0.191 to 0.567) and 0.269 (95% CI, 0.015 to 0.490), respectively. Reduced tongue strength is associated with sarcopenia but is not an exclusive marker for sarcopenic dysphagia. Tongue strength correlates with the values of subcomponents that define sarcopenia. In patients with low performance of sarcopenia subcomponent, tongue pressure must be examined to diagnose subclinical dysphagia.Protocol registration: This meta-analysis was registered on INPLASY (registration number INPLASY202120060).
Sarcopenia, defined as a decline in muscle mass and function related to aging, affects both limb and swallowing-related muscles. Sarcopenic dysphagia is characterized by decreased swallowing function; therefore, early detection of subclinical dysphagia and subsequent intervention appear to be crucial in the elderly. Numerous tools have been employed to measure the function, strength, and mass of swallowing-related muscles in sarcopenic elderly. The swallowing function can be evaluated by questionnaires like Eating Assessment Tool, Functional Oral Intake Scale, and Food Intake Level Scale, and tests such as the modified water swallowing test and videofluoroscopic swallowing study. Surface electromyography and high-resolution manometry can be applied for quantifying swallowing-related muscle strength. Modalities such as ultrasonography and magnetic resonance imaging are capable of estimating the swallowing muscle mass. In patients with sarcopenic dysphagia, a thorough assessment should be given followed by an integrated intervention combining swallowing muscle strengthening, nutrition support, food texture modification, physical, and occupational therapies. This article aimed to comprehensively summarize the diagnostic criteria/tools as well as their associations/performance in sarcopenic dysphagia. The intervention strategy will also be narrated in this review.
We explore an approach for optically pumping a body of optically dense magnetic material. This challenge arises in time-resolved electron paramagnetic resonance (TREPR), triplet-based dynamic nuclear polarisation (DNP), and cavity QED. Crystals of pentacene-doped p-terphenyl were grown around variously shaped ends of optical waveguides, through which pump light could be injected deeply into the crystal. When incorporated into a maser as the gain medium, we found that, compared to conventional side-pumping, 11 times less pump beam intensity was needed to reach the masing threshold and 54 times more pulse energy could be absorbed by the gain medium without damage, resulting in a record peak output power of -5 dBm.
To increase output torque in the constant power region of interior permanent magnet synchronous motor (IPMSM) for electric vehicle/hybrid electric vehicle applications, a novel torque control based on voltage phase angle control is proposed to provide more accurate torque for the IPMSM. First, the mathematic model of the IPMSM under six-step voltage operation is derived. Then, the phasor diagram based on the fundamental frequency and ideal condition is used to explain the relation between the torque, power, and voltage phase angle. Moreover, Maxwell 2D simulation for the IPMSM shows the detailed phenomena including generated torque, phase current, and magnetic flux distribution for developing controllers. Hence, the proposed method uses phase voltage advancing angle to yield torque, which consists of a command feed-forward controller to give a fast dynamic response, a proportional-integral regulator, a high-resolution voltage angle injection to reduce torque ripple and an efficiency-based torque estimator to enhance torque accuracy under six-step voltage operation. Finally, a digital signal processor(DSP)-based motor drive is built to verify the proposed method using a 6 kW/47 Nm/1200 rpm IPMSM. The experimental results measured by a torque transducer are derived to show that the torque ripple is significantly reduced, torque accuracy is improved, and constant power control achieved is from 1800 to 3600 rpm. These results, therefore, confirm the superior performance of the proposed control method.
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