Introduction: Video electroencephalography monitoring (VEM) is the gold standard for differentiating epileptic seizures and psychogenic nonepileptic seizures (PNES). This study aimed to compare the semiologic characteristics of PNES and frontal and temporal seizures. Materials and Methods: This study was conducted retrospectively on the records of patients aged over 18 years with PNES and frontal and temporal lobe seizures, who were followed up as inpatients in the Ufuk University Neurology Clinic VEM unit between 2016 and 2020. Seventy-two patients who met the study criteria and were hospitalized during this period were included in the study. The preictal, ictal, and postictal semiologic characteristics of the patients were examined and compared in terms of the seizure type. Results: Of the 72 patients included in the study, 29.2% had PNES, 15.3% had frontal lobe epilepsy, and 41.7% had temporal lobe epilepsy. The mean age of the patients was 32.74 ± 9.84 years. In patients with PNES, frequent semiologic changes, frequent medical visits, ability to execute commands, remembering test words, forced eye closure, subjective sensory symptoms, ictal crying, tremor in extremities, gradual onset, fluctuating course, postictal pseudo-sleep, pelvic thrusting movement, and arrhythmic synchronous extremity movement manifestations were determined to be significantly higher compared with frontal and temporal lobe epilepsies. Conclusion: Seizure semiology is important in the differential diagnosis of epileptic seizures and PNES. VEM remains the gold standard for differentiating PNES and epileptic seizures.
Background Clinical seizure semiology provides valuable information in the evaluation of focal-onset bilateral tonic–clonic seizures. In the evaluation of these patients, long-term video-EEG monitoring (VEM) and neuroimaging studies are of great significance in determining lateralization together with clinical semiology. In this study, we examined the features of the figure 4 sign that we detected in patients with refractory epilepsy whom we followed up in the VEM unit. Methods In the study, 175 patients followed in the VEM unit were examined. Twenty-two patients for whom the figure 4 sign was detected were included in the study. Patients with the side indicated by the figure 4 sign comply with ictal EEG compatible were named as 1st group (G1), and those not were named as 2nd group (G2). Demographic characteristics, seizure type, number of seizures per month, duration of epilepsy, number of seizures during VEM, duration of figure 4 sign, medical history, and cranial MRI characteristics were compared between the two groups. Results When G1 and G2 were compared, it was observed that temporal lobe seizures were statistically significantly higher in G1. When the figure 4 sign durations were examined, this period was 16.3 ± 8.2 s in frontal lobe seizures and 20.8 ± 7.4 s in temporal lobe seizures. When the duration of the figure 4 sign was examined by gender, it was found that the duration was longer in males, which was statistically significant. Conclusion In conclusion, it is essential to evaluate ictal EEG findings together with brain imaging while performing semiological localization and lateralization in epileptic patients.
Sjogren’s Syndrome (SS) is a chronic autoimmune disorder that may be complicated by neurological dysfunctions. The involvement of cranial nerves in SS was described as a very rare complication. Moreover, bilateral peripheral facial paralysis associated with SS has been described only in 3 patients in the literature and the first case was described by Henrik Sjogren himself in 1935. We report a 59-year-old female with bilateral peripheral facial paralysis associated with Sjogren’s syndrome. She was treated with 5-day IVIG consecutively and continued oral methylprednisolone 16mg/day and almost fully recovered at 2 months of follow-up examination. Acute bilateral peripheral facial palsy in SS is a very rare condition and Lyme disease, Guillain-Barré syndrome, HIV infection, and central nervous system lymphoma should be considered in the differential diagnosis. As a result, SS should be considered as an underlying cause of bilateral facial paralysis.
Neuralgic amyotrophy (NA), also known as Parsonage-Turner syndrome or idiopathic brachial plexopathy, is a multifocal inflammatory neuropathy that usually affects the upper limbs. The classic picture is a patient with acute onset of asymmetric upper extremity symptoms, excruciating pain, rapid onset of multifocal paresis often involving winged scapula, and a monophasic course of the disease. We present an unusual case of recurrent NA characterized first by right brachial plexitis and then isolated left posterior interosseous nerve palsy.
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