Objective  To evaluate the safety, acute and long‐term toxicity and therapeutic activity of an allogenic and an autologous hybrid cell vaccine in patients with progressive metastatic renal cell carcinoma (RCC). Patients and methods  Eleven patients were vaccinated with a lethally irradiated hybrid cell vaccine of allogenic RCC tumour cells fused with major histocompatibility complex class I‐matched and class II‐unmatched activated allogenic lymphocytes. These patients were then followed for a mean of 11 months. Another 13 patients were vaccinated with a hybrid cell vaccine of autologous tumour cells fused with allogenic activated lymphocytes and followed for a mean of 6 months. Results  Six of the 11 patients receiving the allogenic vaccination showed an initial response, with two complete and two partial responses to date. Only three patients who received autologous vaccination responded to treatment. Conclusions  Hybrid cell vaccination is a promising new approach in the treatment of patients with advanced RCC.

This article documents the nature, size, and date of the Neolithic settlement on Tsoungiza at ancient Nemea and reports the results of the ceramic, ground stone tool, archaeobotanical, and human osteological analyses. The results of excavations on Tsoungiza in 1974, 1975, 1981, 1982, and 1984, and a restudy of the finds discovered by Carl W. Blegen in 1925-1926, show that the site was an open-air settlement, not a cave; was much larger than previously known, scattered over an area of 26,000 m 2 ; and was occupied from the Early Neolithic period into the early Middle Neolithic and reoccupied in the Final Neolithic period.

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This article offers a critique of one of the most crucial and controversial pillars of Larry W. Hurtado’s reconstruction of the origins and nature of earliest “Jesus ­devotion.” Unlike most other engagements with Hurtado, this article takes seriously into account all of his published work and not simply his magnum opus, Lord Jesus Christ. Likewise, unlike most other engagements, this article critically focuses on the explanatory relationship between Hurtado’s minimalist account of the Christology of Jesus and his earliest disciples and the postulation that powerful Easter and post-Easter “religious experiences” played the key role in the origins of Jesus devotion. Essentially, this article contends that Hurtado’s persuasive case concerning the very early origins of Jesus devotion (perhaps, so he argues, to be dated as early as the first few months of the post-Easter period) ought to have pushed his search for the major causes of such devotion back beyond the “religious experiences” of post-Easter Christians and into the life of the historical Jesus himself.

Encyclopaedia Judaica (2nd Edition 2007) eBook version of 22 volume print encyclopedia, covering all aspects of the Jewish world and Judaism.