Large convolutional neural network models have recently demonstrated impressive performance on video attention prediction. Conventionally, these models are with intensive computation and large memory. To address these issues, we design an extremely light-weight network with ultrafast speed, named UVA-Net. The network is constructed based on depth-wise convolutions and takes low-resolution images as input. However, this straight-forward acceleration method will decrease performance dramatically. To this end, we propose a coupled knowledge distillation strategy to augment and train the network effectively. With this strategy, the model can further automatically discover and emphasize implicit useful cues contained in the data. Both spatial and temporal knowledge learned by the high-resolution complex teacher networks also can be distilled and transferred into the proposed low-resolution light-weight spatiotemporal network. Experimental results show that the performance of our model is comparable to 11 state-of-the-art models in video attention prediction, while it costs only 0.68 MB memory footprint, runs about 10,106 FPS on GPU and 404 FPS on CPU, which is 206 times faster than previous models.

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Background Vitamin B12 takes essential effects on human reproductive system. The impact of Vitamin B12 on the outcome of assisted reproduction technology (ART) still remains elusive. This study was aimed to investigate whether vitamin B12levels is associated with the outcomes of IVF-ET. Methods A retrospective study was carried out in an assisted reproduction unit in a Chinese teaching hospital, from November 2018 to December 2019. A total of 356 infertile women, aged 20–45 years, were included. The patients were classified by vitamin B12 status: deficient (B12< 298 pg/ml) and normal (298-350 pg/ml), sufficient (B12 > 350 pg/ml). Linear regression and smooth curve fitting were performed to analyze the association between Vitamin B12 and the outcomes of IVF-ET. Result(s) We found a nonlinear relationship and threshold effect between serum vitamin B12 and the outcomes of IVF-ET, after adjusting for various potential confounding factors. When the vitamin B12 value is lower than 357.1 pg/ml, the vitamin B12 is significantly positively related to the clinical pregnancy outcomes, each 10 pg/ml increase in the vitamin B12 value, the clinical pregnancy rate increased by 4% (OR=1.04, 95% CI=1.00, 1.09, P=0.0337), When the vitamin B12 value is greater than 357.1 pg/ml, the vitamin B12 is not significantly related to the clinical pregnancy outcomes (P>0.0337). Conclusion(s) Lower serum vitamin B12 levels are associated with a lower clinical pregnancy rate in IVF, for the normal and deficient vitamin B12 Chinese infertile women who undergo IVF-ET with the follicular-phase GnRH agonist protocol.

Research question: What are the influencing factors of the average blastomere number of all embryos in D3 patients and the association with a live birth rate in the transfer cycle? Methos: A total of 7420 fresh embryo transferred cycles of patients who underwent IVF-ET in the Reproductive Medicine Center, Renmin Hospital, Hubei University of Medicine from January 2016 to December 2021 were selected retrospective observed. Results: According to the average blastomeres number in all embryos on day 3 following oocyte retrieval, the patients were split into five groups: 5.00 group (747 cases), 5.01-6.00 group (1763 cases), 6.01-7.00 group (3052 patients), 7.01-8.00 group (1646 cases), and >8 groups (212 patients). The average number of blastomere on D3 was negatively associated (P <0.05) with infertility, duration infertility, male factors infertility, E2 value on hCG day, and ICSI insemination method. The live birth rate(LBR) of the groups 5.00 and 5.01-6.00 was considerably lower than that of the other groups, according to multivariate regression analysis（P＜0.001). Further additional curve fitting was utilized to demonstrate that the LBR increased significantly as the number of blastomeres grew, increasing a value of 20% for every different blastomere number when the average number of blastomeres on D3＜5.7 (P<0.001). On the other hand, when the number≥5.7 (P=0.258), the live birth rate no longer increases. Conclusion: An average blastomere number between 7.01 and 8.00 is associated with higher LBR in D3 fresh embryo transfer cycle, when the average blastomeres in D3 embryos are less than 5.7 to reduce the live birth rate of the transfer cycle.

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