A prospective observational study was conducted among 500 women aged 17-27 years to assess the prevalence and severity of Premenstrual syndrome (PMS) and Premenstrual Dysphoric Disorder (PMDD) in a private institution in Kumarapalayam during the period of six months (May 2017-October 2017). The study was done among healthcare and non-healthcare students and the results were compared. One healthcare (H=250 students) and two non-healthcare (NH=250 students) colleges were approached. Chi square test was done to find any difference between the variables and p<0.05 was considered as statistically significant. Out of the 478 participants 7.3% of the total population was using hormonal supplementations. Mood swings was the most common symptom and is severe in around 22% of total study sample. The prevalence of PMDD was 8(3.2%) and 11(4.8%) for non-healthcare and healthcare students respectively. The total prevalence of PMDD in the study population was found to be 3.97%. Based on our study the healthcare students reported higher percentage of moderate to severe symptoms than non-healthcare students. The prevalence of PMDD was also found to be higher in healthcare institution