Objective We compared the performance of color Doppler twinkling artifacts with B-ultrasound and computed tomography (CT) for diagnosis of ureteral calculus in patients with acute renal colic. Methods The location and size of ureteral stones in 2268 patients with acute renal colic were determined using the two ultrasound methods and CT. All cases were followed up for 2-8 weeks. Results Color Doppler twinkling artifacts had a sensitivity of 96.98%, specificity of 90.39%, positive predictive value (PPV) of 99.77%, and negative predictive value (NPV) of 41.23%. B-Ultrasound had a sensitivity of 96.39%, specificity of 80.77%, PPV of 99.53%, and NPV of 34.43%. CT had a sensitivity of 99.59%, specificity of 94.23%, PPV of 99.86%, and NPV of 84.48%. The area under the receiver operating characteristic curve was 0.925 for color Doppler twinkling artifacts, 0.863 for B-ultrasound, and 0.963 for CT. Conclusion For the diagnosis of ureteral calculus, the sonographic twinkling artifact had a similar performance as CT. We suggest use of the sonographic twinkling artifact instead of CT for patients with acute renal colic to reduce the examination time and exposure to radiation, and to provide earlier access to treatment.

Multilocular cystic renal neoplasm of low malignant potential (MCRNLMP) might be benefited from nephron-sparing surgery. Contrast-enhanced computed tomography is used for the diagnosis of MCRNLMP but contrast-enhanced ultrasound has lack of nephrotoxicity and several advantages over contrast-enhanced computed tomography and contrast-enhanced magnetic resonance. The purpose of the study was to compare diagnostic parameters of preoperative contrast-enhanced ultrasound against contrast-enhanced computed tomography for the detection of MCRNLMP in patients who faced curative surgery for complex cystic renal mass. Data regarding contrast-enhanced ultrasound, contrast-enhanced computed tomography, and clinicopathological results of 219 patients who underwent curative surgery for complex cystic renal mass (Bosniak classification III or IV) were retrospectively collected and analyzed. Bosniak classification for imaging modality and the 2016 WHO criteria for clinic pathology were used for detection of MCRNLMP. Contrast-enhanced ultrasound, contrast-enhanced computed tomography, and clinicopathology were detected 68, 66, and 67 as a MCRNLMP respectively. Contrast-enhanced ultrasound and contrast-enhanced computed tomography had 30.37% and 29.27% sensitivities for the detection of MCRNLMP. While 60% and 50% specificities respectively. Bosniak classification III ( P = .045) and lower mean Hounsfield unit ( P = .049) were associated with the prevalence of MCRNLMP. Contrast-enhanced computed tomography was detected 6 and 7, while contrast-enhanced ultrasound detected 3 and 2 complex cystic renal mass as false positive and false negative MCRNLMP respectively. A contrast-enhanced ultrasound had 0.011 to 1.0 diagnostic confidence and contrast-enhanced computed tomography had 0.045 to 0.983 diagnostic confidence for decision making of nephron-sparing surgeries. Contrast-enhanced ultrasound may have better visualization of MCRNLMP than contrast-enhanced computed tomography. Level of Evidence: III.